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view File Ed View Go Tools Window Help Unit 2 Exam Review PPT 1 (2).ppt (page 11 of 24) Search 10. Generation I antihistamine
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Answer is true .Tha H1 antagonist means conventional antihistaminics agents.These drugs antagonized the actions of histamine at the H1 receptors.This compounds are ability to penetrate blood -brain barrier and affinity for the central H1 receptors.Due to antagonism of histamine in the brain or reflects antimuscarinic property of these drugs .

Examples are Promethazine,Hydroxyzine .

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