Question

Uses of SSRI's including withdrawal and monitoring of effect Anti-lipidemics mechanism of action and uses (Chapter 16) Cardiac glycosides uses and monitoring Drug interactions with diuretics (loop and distal tubular) and their uses ACEi clinical uses and mechanism of action (especially in angina, post MI and heart failure

Answer 1

SSRI uses, withdrawal, monitoring:
   SSRIs is an antidepressant, it treats depression, generalized anxiety disorder, obsessive-compulsive disorder, bulimia, phobias, PTSD. To lower the risk of SSRI discontinuation syndrome like dizziness, fatigue, diarrhea, chills, headache, nausea, suicidal thoughts, psychosis. Wean the drug gradually if you take treatment for less than eight weeks, tapering off with one to two weeks. It 6 to 8 months taper for six to 8 weeks. Monitoring needed with a systemic assessment of symptoms and address effects adherence therapy, medication functions are important. for the full effect, treatment should be continued for 4 to 9 months. Monitor the patient for several months after discontinuation. If symptoms reoccur another course of treatment for acute-phase they should continue.
Anti-lipidemic:
It is a lipid-lowering drug by reducing cholesterol biosynthesis in the liver with the effect of inhibition on the HMG-CoA reductase.
It prevents atherosclerosis formation in the arteries.
Cardiac glycosides use and monitoring:
    Cardiac glycosides used to treat congestive heart failure and atrial fibrillation. It inhibits the membrane sodium-potassium Na+ K+ pump, raising intracellular sodium+. Close monitoring of serum concentration is important. Overdose can be life-threatening and monitoring the patient for nausea, vomiting, blurred vision, and arrhythmias.
Diuretics drug interaction and uses:
Diuretics are a class of drugs that increase the flow of urine by removing sodium and chloride from the body in the urine and remove excess water from the body.
Loop diuretics are an important diuretic that increases the elimination of sodium and chloride by preventing reabsorption of sodium and chloride. This involves a portion of renal tubule for high efficacy...
In distal tubule, potassium is excreted from urine for reabsorption of sodium. potassium-sparing diuretics reduce sodium reabsorption at the distal tubule, it decreases potassium secretion, it is combination therapy with loop diuretics.