Question

You are asked to prepare 2 liters of a 1:500 solution of povidone iodine. You find that you carry the product pictured below. 1. How many milliliters of the povidone iodine solution pictured below should you use to compound this prescription? NOC 0503-1550-56 POVIDONE IODINE 10% SOLUTION TOPICAL ANTISEPTIC BACTERICIDE FOR USE IN MINOR SKIN WOUND SCRAPES CUTS HET BOE (231 Qualitest II. What is the percent concentration of the preparation of povidone-iodine 1:500 solution that you compounded?

Answer 1

Required prescription volume of povidone-iodine solution is 2 litres or 2000ml

The required prescription solution is 1:500 which means the solute : solution should be equal to 1:500.

It means 1 ml of solute should be present in 500 ml solution.

It means for 2000 ml prescription solution the solute required is 4 ml.

I

The available solution is 10% povidone-iodine solution. It means 10ml of povidone-iodine is present in 100ml of this solution.

It can be taken as 1 ml of povidone-iodine in 10 ml solution.

The required volume of povidone-iodine = 4 ml

It is present in 40ml solution.

40 ml of povidone-iodine solution pictured is required to compound the prescription.

II

The percent concentration of the preparation of compounded povidone-iodine solution =

( volume of povidone-iodine required * 100 / total volume of prescription )

which is ( 4 * 100 / 2000 ) = 1/5

which is 0.2 %

The v/v percent concentration of the preparation compounded is 0.2 %

This is a brief explanation. Hope this helps you out. Please feel free to give a like and contact us if you need further detailed explanation. Thank you and have a great day.