Question

To reconstitute a 100 mL bottle of Augmentin for oral suspension 400mg/5 mL, the manufacturer recommends 90 mL of distilled water is added in two divided portions. First loosen the powder in the bottle, then add approximately 1/3 of the total volume of water and shake the suspension. After the powder is wet, add the remaining water. How much water should you add each time?

Answer 1

Here , manufacturer recommend to add total 90 ml of distilled water in two times.

First add 1/ 3 rd of total water means divide 90 ml water by 3

That is, 90/ 3= 30 ml

Second step is after wetting the powder, add remaining distilled water,

It is, 90 - 30 = 60 ml