Question

can someone help me with the complications, contraindications/precautions, interactions for the Hepatitis B vaccine and NOT the Hepatitis B immune globulin.

Answer 1

Hepatitis B vaccine is a Bio synthesized vaccine which is same as hepatitis virus but it is safe to use because it is not a live virus.

Complications

Hepatitis vaccine is a very safe vaccine and having a very rare complication.

The common side effects are

• Sore, redness, and pain in the injection site
• High body temperature
• Nausea
• vomiting
• diarrhea
• stomach ache
• Sore throat
• Upper respiratory infection
• headache

The serious complication is very rare, it includes

• Severe pain and swelling at the injection site
• Joint pain
• rashes
• Anaphylactic shock
• Hypotension

Contractions

If there is any previous history of anaphylaxis with Hepatitis B vaccines.

Precautions

Do not use the same syringe for two or more vaccines.

Adjust the dose for premature baby(Weight less than 2000grams) and calculate potential benefits and risk befor administer.

Give special attention to the individual with hemophilia or other bleeding disorders during giving injection because it can cause intramuscular and intradermal bleeding.

Interaction

Hepatitis vaccine can interact with 37 different drugs, they are classified in mild, moderate and severe

Severe reaction with belimumab

Moderate reaction with mercaptopurine, daclizumab, methotrexate, and hydroxyurea.

It can maybe interact with cloroquine drug.