An 89 year old F (62", 59 kg) is admitted to the MICU for hypotension and...

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An 89 year old F (62, 59 kg) is admitted to the MICU for hypotension and is started on a Levophed® (norepinephrine) drip at One day later, you notice that the Levophed® drip as prepared above is infusing at 60 ml/hr. The MD has requested that you ad

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Answer 1

Answer #1

I.

Patient dose = 4 mcg/minute

If we calculate it for an hour, dose = 4mcg×60 minutes

= 240 mcg/ hour

Available infusion concentration given by pharmacy technician = 4mg/250ml of NS

=4000mcg/250ml of NS (1mg = 1000mcg)

Each mL contain = 4000/250

=16 mcg/ml

Required fluid in mL/ hour = Required dose/ available dose

= 240mcg/hour ÷ 16 mcg/mL

= 15mL/hour

So that nurse should run 15ml of NS per hour to deliver the dose at the rate of 4mcg/ min

II.

On the second day levophed drip is running at the rate of 60 mL/ hour

MD requested you do adjust the levophed concentration to deliver same dose with 20ml/ hour.

Which means that adjusted levophed drip concentration should be 3 times (60/20 = 3)more than previous concentration.

Previous concentration =4mg/250ml of NS

Current concentration=4mg×3/250 ml of NS

= 12mg/250ml of NS.

12 mg of levophed should be mixed in 250 ml of NS

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Answer 2

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