Question

this is the whole questions.

3. The prescriber orders 500 mg amoxicillin IVPB q8 hr for a patient with an infection. The recommended safe and therapeutic dosage of amoxicillin is 20-40 mg/kg/day divided in equal doses q8 hr. The patient's current weight is 75 pounds. The 500 mg of amoxicillin is contained in a 100 mL bag of normal saline and is to be infused over 1.5 hours. Calculate the safe "single dose range" for each 8 hour dose (mg/dose). Round to the nearest tenth or hundredth if needed. bd If the ordered dose is safe, at what rate will the RN set the electronic infusion device in milliliters per hour? Round answer to the whole number.

please show me the formula ang how to solve it thank u

Answer 1

1. We have calculated dose in kg So, lets converted pound to kg

1 pound = 0.454 kg

75 pound ( $75\times 0.454= 34.05$ kg) Round figure is 34kg

2. Recommended daily therapeutic dose is 20-40 mg/kg/day

$20mg\times 34kg= 680mg$/day to $40mg\times 34kg= 1360mg$ /day

The daily safe therapeutic dose should range from 680mg to 1360 mg per day

3. Equal distribution per dose

$680\div 3= 226.66$mg (230 mg) to $1360\div 3= 453.33$ mg (450mg)

    Ans.  single dose will be range from 230mg to 450mg

4. Rate of infusion

Above mention rate should be 500ml in 1.5 hr(90 minutes)

so rate in the infusion device will be 333ml per hr

$500ml\div 90min= 5.5555$ml in 1 minute

$5.5555ml\times 60min= 333.33$ml