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The physician writes an order for heparin 900 units/hr. The label on the I.V. bag reads:...

  1. The physician writes an order for heparin 900 units/hr. The label on the I.V. bag reads: Heparin 10,000 units in 500 mL D5W. How many mL/hr will deliver the correct dose?
  1. The Order: Amoxicillin 125 mg p.o. every 8 hours for 10 days. The child weighs 40 pounds. Label reads: 125mg/5mL. Safe range is 20-40 mg/Kg/day in divided doses q8h. What is the safe dose range for this child? (round to nearest whole numbers)

Is this dose safe?

  1. Give Regular insulin by continuous I.V. infusion at 20 units/hr. The solution is 250 mL NS with 250 units of Regular insulin. How many mls/hr. will deliver the correct dose?
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Answer #1

ANSWER.

* Calculation of ml/hr.

      ml/hr = Volume(ml) / Time(hr).

      Calculation of volume(ml)

          Volume(ml) = Desired dose /Dose in hand * Quantity.

     Here

          Desired dose (D) = 900 units.

          Dose in hand (H) = 10000 units.

              Quantity (Q) = 500 ml

    As per above formula

        Volume(ml) of drug required = D/H * Q

                                                      = 900/10000 * 500

                                                      = 0.09 * 500

                                                      = 45 ml.

                                 Time(hr) = 1 hour.

           So

                    ml/hr = 45 ml/hr.

* Calculation of safe dose.

          Ordered dose = 125 mg P.O Q8H.

           Weight of the patient = 40 pounds.

       Convert pound o kg for calculation

               1 pound = 0.45 kg

        So

            Weight of the patient = 40 * 0.45

                                               = 18 kg.

          Safe dose required for a child weight 18 kg = 20 * 18 - 40 * 18

                                                           = 360 mg - 720 mg/day divided doses (Q8H).

                   Ordered dose = 125 mg every 8 hrs or three times a day.

                                           = 125 * 3

                                           = 375 mg per day.

   * So ordered dose is safe for this patient.

* Calculation of ml/hr.

        ml/hr = Volume(ml) /Time(hr)

      Calculation of volume(ml)

           Volume(ml) = Desired dose /Dose in hand * Quantity.

      Here

           Desired dose (D) = 20 units.

           Dose in hand (H) = 250 units.

              Quantity (Q) = 250 ml

As per above formula

          Volume(ml) of drug required = D/H * Q

                                                        = 20/250 * 250

                                                        = 0.08 * 250

                                                        = 20 ml

                           Time(hr) = 1 hour.

              So

                       ml/hr = 20 ml/hr.

              

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