Question

Q23. What is the probable cause of myasthenia gravis? A) excessive synthesis of cholinergic receptors B) inadequate synthesis of cholinergic receptors C) failure of acetylcholine reuptake system D) binding of antimuscarinic receptor antibodies to the muscarinic cholinergic receptor E) binding of anti-nicotinic receptor antibodies to the nicotinic cholinergic receptor Q24. M and N receptors and their locations throughout the body??

Answer 1

Ans) 23)C) failure of acetylcholine reuptake system

Explaination:

Acetylcholine causes muscles to contract, activates pain responses and regulates endocrine and REM sleep functions. Deficiencies in acetylcholine can lead to myasthenia gravis, which is characterized by muscle weakness.

24) Muscarinic acetylcholine receptors, or mAChRs, are acetylcholine receptors that form G protein-coupled receptor complexes in the cell membranes of certain neurons[1] and other cells. They play several roles, including acting as the main end-receptor stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system.

- Nicotinic acetylcholine receptors, or nAChRs, are receptor polypeptides that respond to the neurotransmitter acetylcholine. Nicotinic receptors also respond to drugs as the agonist nicotine.

- Muscarinic Receptors in the brain, heart, smooth muscle, or in the Parasympathetic nervous system. While Nicotinic Receptors are found in the Sympathetic nervous system, Muscarinic receptors are not. This is the crucial difference.