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13. What is the most widely accepted theory as to how HIV evolved? (A) Viral recombination in a chimp infected with multiple
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13. Answer is D

Reason: The closest relatives of HIV-1 are simian immunodeficiency viruses (SIVs) infecting wild-living chimpanzees and gorillas in west central Africa. More than 40 species of African monkeys are infected with their own, species-specific, SIV and in at least some host species, the infection seems non-pathogenic. Chimpanzees acquired from monkeys two distinct forms of SIVs that recombined to produce a virus with a unique genome structure. Recombination of SIV causes CD4+ T-cell depletion and increases mortality in wild chimpanzees.

14. Answer is B

Reason:

AIDS (acquired immunodeficiency syndrome),

HIV virus kills CD4+ cells

AIDS diagnosed by the isotypes of free antibodies to HIV-1, IgM, IgG, IgA, and IgE. IgG (IgG1, IgG2, IgG3, and IgG4) and IgA (IgA1 and IgA2).

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