A 70-kg adult patient is being treated for iron poisoning. He is administered desferrioxamine mesilate initially...
A 70-kg adult patient is being treated for iron poisoning. He is administered desferrioxamine mesilate initially at a dose of 12 mg/kg per h to be reduced by 25% after 6 h. How much desferrioxamine mesilate will this patient have received after 12 hours of therapy?
Homework Answers
Weight of the patient = 70 kg
Desferrioxamine mesilate initially at a dose of 12 mg/kg per
As per weight of the patient required dose= 70 X 12= 840 mg per hr.
For initial 6 hours the amount will be= 840 X6=5040 mg
As stated after after 6 hours reduce the dose 25 %
Means 25% of 840= 210 mg
hence the applicable dose per hr will be = 630 mg/hr
Hence for remaining 6 hous the amount of the drug deliverd will be= 630x6=3780 mg
Thus the patient have received dose/amount after 12 hours will be = 5040+3780
= 8820 mg or 8.820 g
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