You're studying the organization of mitochondria. Your PI hypothesizes that their spread-out organization throughout the cells depends on microtubules. Which of the following experiments will best test his hypothesis?
| Treat cells with the microtubule stabilizing drug taxol and monitor the organization of mitochondria by immunofluorescence. |
|
Treat cells with the microtubule-depolymerizing drug nocodazole and monitor the organization of mitochondria by immunofluorescence. |
| Treat cells with the microtubule-depolymerizing drug nocodazole and monitor the organization of microtubles by immunofluorescence |
| Express GFP-tagged α-tubulin and an RFP-tagged subunit of ATP Synthase |
| Disrupt kinesin function and monitor mito organization by immunofluorescence. |
Answer:
The experiment with best hypothesis treatment of cell with drug nocodazole that is microtubule de polymerizing drug and then monitor the mitochondrial organization by immunofluorescence.
Hence,option(b) is correct.
You're studying the organization of mitochondria. Your PI hypothesizes that their spread-out organization throughout the cells...