1- Suggest a retrosynthetic analysis for each of the following target molecules In each case identify...
1- Suggest a retrosynthetic analysis for each of the following target molecules
In each case identify the latent polarity and the type of disconnection .
2-suggest synthons, synthetic equivalents, and reagents for the forward synthesis (a single disconnection is required )
((resynthetic steps) , ((synthetic steps))
Homework Answers
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1- Suggest a retrosynthetic analysis for each of the following
target molecules
In each case identify...
A) at least one retrosynthetic analysis (disconnection) B) a reaction scheme showing each of the synthetic...
A) at least one retrosynthetic analysis (disconnection) B) a reaction scheme showing each of the synthetic steps with starting materials, products, reagents and conditions C) a paragraph or so describing the logic of a synthetic strategy and why it would be the most likely to give the desired product. octa-2,4,6-triene
For any two of the molecules below, outline both a retrosynthetic analysis and a forward synthesis...
For any two of the molecules below, outline both a retrosynthetic analysis and a forward synthesis with reagents. Each of your building blocks should not incorporate more than five carbon atoms of the target molecule. (Note: your syntheses do not need to be stereoselective) COH OH [20 marks]
6. (12 pts) For each the molecules below, provide a retrosynthetic analysis and then give a...
6. (12 pts) For each the molecules below, provide a retrosynthetic analysis and then give a step-by- step synthetic plan. All the carbon atoms in the final products must come from molecules in the box at the bottom. You may use any other reagents you want to accomplish your synthesis. H3CH2CO Acceptable Carbon Sources: " i hool.com ormar BCH,NH iicuch " OCH CH3
The picture below is an example of how this assignment should be done. This experiment involves...
The picture below is an example of how this assignment should be
done.
This experiment involves the synthesis of a target molecule using Grignard reagents. You must do the following: 1. Perform a retrosynthetic analysis on the target molecule. The organic starting material (what you have to work backwards toward) is provided. Draw a retrosythetic scheme; use the rightwards double arrow to show functional group transformations and disconnections. Provide synthons and synthetic equivalents for every disconnection made. 2. Propose the...
4. (12 pts) For each of the molecules below, provide a retrosynthetic analysis to starting materials...
4. (12 pts) For each of the molecules below, provide a retrosynthetic analysis to starting materials that satisfy the conditions given. Then give a step-by-step synthetic plan. You may use any reagents you want to accomplish your synthesis. HC НОХ H₃C CH весна from propanal as the only carbon source from starting materials containing three or fewer carbon atoms
Propose a synthesis using the target molecule with retrosynthetic analysis. Provide complete reagents for each step of your proposed synthesis. from Target molecule from Target molecule
Propose a synthesis using the target molecule with
retrosynthetic analysis.
Provide complete reagents for each step of your proposed
synthesis.
from Target molecule
from Target molecule
Page 1 Synthesis using Carbonyl O-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules...
Page 1 Synthesis using Carbonyl O-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry. You are assigned two target molecules, one of which is best synthesized by an alkylation approach, while the other is best synthesized by an addition or condensation approach. You must do the following: 1. Perform a retrosynthetic analysis on the two target molecules assigned to you. In each case the organic starting material (what you have to work backwards toward) depends...
Question 1 Ph н он (a) Give a detailed one step retrosynthetic analysis of Compound A...
Question 1 Ph н он (a) Give a detailed one step retrosynthetic analysis of Compound A based on Grignard chemistry and in the process identify two possible routes for its synthesis (2 marks) (b) Give all reagents and conditions for a synthesis of A based on one of your answers to part (a) (2 marks) (c) Would you expect A to form as a single stereoisomer? Explain your answer (2 marks) (Total for question 1 = 6 marks)
Question 1...
Synthesis using Carbonyla-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry....
Synthesis using Carbonyla-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry. You are assigned two target molecules, one of which is best synthesized by an alkylation approach, while the other is best synthesized by an addition or condensation approach. My two target molecules are number 2 and number 12 in the last page. You must do the following: 1. Perform a retrosynthetic analysis on the two target molecules assigned to you. In each case the...
Retrosynthetic Analysis 12. Give a reasonable synthesis for each of the following compounds from the indicated...
Retrosynthetic Analysis 12. Give a reasonable synthesis for each of the following compounds from the indicated starting materials. You may use any other organic or inorganic reagents you wish unless otherwise indicated. The desired product for each reaction you propose must be the one of the predominant products. Give the reactants, conditions (where appropriate) and products of each synthetic step. NO MECHANISMS! [8 points] NH ONH2 Make starting with
For any two of the molecules below, outline both a retrosynthetic analysis and a forward synthesis with reagents. Each of your building blocks should not incorporate more than five carbon atoms of the target molecule. (Note: your syntheses do not need to be stereoselective) COH OH [20 marks]
6. (12 pts) For each the molecules below, provide a retrosynthetic analysis and then give a step-by- step synthetic plan. All the carbon atoms in the final products must come from molecules in the box at the bottom. You may use any other reagents you want to accomplish your synthesis. H3CH2CO Acceptable Carbon Sources: " i hool.com ormar BCH,NH iicuch " OCH CH3
The picture below is an example of how this assignment should be
done.
This experiment involves the synthesis of a target molecule using Grignard reagents. You must do the following: 1. Perform a retrosynthetic analysis on the target molecule. The organic starting material (what you have to work backwards toward) is provided. Draw a retrosythetic scheme; use the rightwards double arrow to show functional group transformations and disconnections. Provide synthons and synthetic equivalents for every disconnection made. 2. Propose the...
4. (12 pts) For each of the molecules below, provide a retrosynthetic analysis to starting materials that satisfy the conditions given. Then give a step-by-step synthetic plan. You may use any reagents you want to accomplish your synthesis. HC НОХ H₃C CH весна from propanal as the only carbon source from starting materials containing three or fewer carbon atoms
Propose a synthesis using the target molecule with
retrosynthetic analysis.
Provide complete reagents for each step of your proposed
synthesis.
from Target molecule
from Target molecule
Page 1 Synthesis using Carbonyl O-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry. You are assigned two target molecules, one of which is best synthesized by an alkylation approach, while the other is best synthesized by an addition or condensation approach. You must do the following: 1. Perform a retrosynthetic analysis on the two target molecules assigned to you. In each case the organic starting material (what you have to work backwards toward) depends...
Question 1 Ph н он (a) Give a detailed one step retrosynthetic analysis of Compound A based on Grignard chemistry and in the process identify two possible routes for its synthesis (2 marks) (b) Give all reagents and conditions for a synthesis of A based on one of your answers to part (a) (2 marks) (c) Would you expect A to form as a single stereoisomer? Explain your answer (2 marks) (Total for question 1 = 6 marks)
Question 1...
Synthesis using Carbonyla-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry. You are assigned two target molecules, one of which is best synthesized by an alkylation approach, while the other is best synthesized by an addition or condensation approach. My two target molecules are number 2 and number 12 in the last page. You must do the following: 1. Perform a retrosynthetic analysis on the two target molecules assigned to you. In each case the...
Retrosynthetic Analysis 12. Give a reasonable synthesis for each of the following compounds from the indicated starting materials. You may use any other organic or inorganic reagents you wish unless otherwise indicated. The desired product for each reaction you propose must be the one of the predominant products. Give the reactants, conditions (where appropriate) and products of each synthetic step. NO MECHANISMS! [8 points] NH ONH2 Make starting with
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