Pick one (neutralization, opsonization, or complement fixation) and describe the role of the antibody.
Opsonization
pathogens have PAMP (pathogen Associated Molecular Pattern) on the membrane which is recognized by the opsonins proteins like Antibodies. Cell like neutrophils, macrophage and monocytes are not able to recognize and bind directly to the all PAMPs present on the surface of pathogens hence needs the assistance by other cells in order to destroy the pathogen. Antibodies bind to the PAMP by the Fab fragment which has antigen-binding sites by the process known as opsonization and makes them susceptible to phagocytosis. The Fc portion of antibodies remains free. Macrophages, monocytes, and neutrophils have the receptor for the Fc portion of antibodies and bind to the antibodies already bounded with the pathogen this causes the phagocytosis of the antibodies bound pathogen.
Pick one (neutralization, opsonization, or complement fixation) and describe the role of the antibody.
1. Opsonization involves: Select one: a. The binding of an antibody to an epitope on a pathogen b. Rearrangement V and J regions of the light chain locus c. Recombination of different V, D, and J regions of the heavy chain locus d. Expression of MHC Class I proteins on all nucleated cells for recognition of self e. Subtle mutation of the heavy and light chain genes to optimize antibody structure 2. Which of these produces and secretes antibodies in...
The binding of an antigen to an antibody can result from all of the following except complement activation opsonization agglutination or precipitation activate T cells. neutralization of the antigen
Describe in detail the complement system (Classical, alternative and Lectin/Mannan pathway); include opsonization, MAC and inflammation.
Which of the following is not a function of complement? a)Stimulate inflammation b)Cytolysis of bacteria c)Neutralization of viruses d)Opsonization THE ANSWER IS NOT A DO NOT ANSWER IT WITH A! A IS WRONG!
2s Antigen-Antibody interactons ooour in which of the foliowing ways? A Opsonization BNecation A D. Complement Fixation EAl the above are cormect 26 Antigen binding sites of an anibody are locaed in the A. Light chains alone D. Fab regions of the antbody B Heavy chains sioneCF ion of the antbody E. Soft chains alone 27 Nonspecific chemical defenses include D stomach hydrochlorie acid A. lysozyme E. All of the choices are corredt Blacic acid and electrolytes of sweat Cskins...
Describe the role of the complement cascade in non specific immunity.
The first layer of protection is: Antimicrobial peptides. Skin. Macrophages. B cells. Which complement pathway generates the membrane attack complex (MAC)? Lectin pathway. Classical pathway. Alternative pathway. All of the above. Antibodies function by: Neutralization. Opsonization. Complement activation. All of the above. The function of the variable region of the antibody is to: Signals through B cell receptor. Binds to antigens. Binds to Fc receptors. Both a and c. B cells develop in the: Blood. Bone. Thymus. Tissues. Compare and...
22Can you answer that one for me please the order at Falls in ) Antigen presentation, lympocyte development, lym antigen presentation, lymphocyte challenge, lymph lymphocyte development, antigen presentation, lyn lymphocyte challe n ge, antigen presentation, lymph hich process in volves antibodies coating microorgan is agglutination neutralization complement fixation -) anamnestic response -) opsonization Which proce ss involves antibodies covering surface rec
Question VII. While working on an adenovirus vaccine, you perform complement fixation assays to determine semiquantitatively the titers of anti-viral antibody in the serum of subjects following vaccination. You are using the typical version of CFT, in which you add a standard amount of viral antigen and complement to serial dilutions of the subjects’ sera, in which complement was heat-inactivated and then adding sRBC. Your results for three subjects are shown below: Based on these results, assess each subsequent statement...
Describe what an f-tag is? Pick one and describe it in detail