Question

12. X-ray crystallographic analysis of an unidentified receptor showed a pentameric structure, where each subunit contains four transmembrane domains. Out of the following agonists, which is most likely to cause a signalling event when bound to the receptor? a. Acetylcholine b. Insulin c. Melanin-concentrating hormone d. Adrenaline

Answer 1

Ans:-.

Given :- X-ray crystallographic analysis of an unidentified receptor showed a pentameric structure ,where each structure contains 4 transmembrane domain .

This receptors contains prototypic ligated gated ion channels also known as nicotinic acetylcholine receptors.

Mainly found in skeletal muscle.

Ans :- Acetylcholine