For Drosophila, let’s consider three genes a, b, and c. We know where a and b...
For Drosophila, let’s consider three genes a, b, and c. We know where a and b are located, and have a nice idea about c. You conduct a three-point cross to figure it out for sure. We’ll use a, b, & c to refer to the three mutants, and + to refer to the wild-types. Here are the progeny counts from a heterozygote by homozygous mutant wild-type: a, b, c: 770 +, +, +: 384 a, +, +: 80 +, b, c: 86 +, b, +: 304 a, +, c: 292 +, +, c: 12 a, b, +: 16 a) What are the order of the genes on the chromosome and the map distances between them?
Solve problem number 21 in your text, which also involves a
three-point cross (p. 146; note that the
total should be 223, not 213). What are the order of the genes on
the chromosome and the map
distances between them? Note that we used a cis arrangement for all
three genes in the heterozygote
from three-point cross above (#6). That might not always be the
case (the heterozygote might be in
trans arrangement.
Homework Answers
A) The greater number are of parental type offspring and the lowest number of double cross over type offspring.
We know that during double cross over, the middle gene is swapped between the homologous chromosome.
Now the parental types are a b c / +++
And the double cross over type is ++c and ab+
When we compare the parental and double cross over type, when we found that c gene is swapped. Hence the c gene is in the middle.
Order of gene. Is a c b.
B) The genetic distance is calculated by( SCO+ DCO)/ total × 100
Total individuals are 1944
The genetic distance between A and C is
= {(80+86+12+16)/1944}×100=
9.979 or 9.98 centiMorgan.
The genetic distance between c and b is:
={ (292+304+12+16)/1944}×100= 32.098 or 32.1centiMorgan.
The genetic map is:
Add Answer to:
For Drosophila, let’s consider three genes a, b, and c. We know
where a and b...
Mapping genes with recombination frequencies in Drosophila 1. Suppose you know of three linked loci on...
Mapping genes with recombination frequencies in Drosophila 1. Suppose you know of three linked loci on the Drosophila X chromosome (a, b, and c). Assume that you are starting out with true-breeding stocks that show all three recessive traits and true-breeding stocks that show all three dominant traits. A. If you wanted to do a 3-point test cross to map the three loci, how would you set up the cross? What genotypes do you use for males and females in...
4. There are three genes on the X-chromosome in drosophila, yellow (y), white (w), and cut...
4. There are three genes on the X-chromosome in drosophila, yellow (y), white (w), and cut (ct). A yellow-bodied, white-eyed, and a homozygous normal winged female fly was crossed to a male with wild type body, wild type eyes, and cut wings. The Fi females were wild type for all three traits, while the Fi males had yellow bodies, white eyes, normal wings. The Fi females were crossed to yellow bodied, white eyed, cut wing males. The resulting F2 progeny...
43. Genes a and b are X-linked and are located 7 mu apart on the X...
43. Genes a and b are X-linked and are located 7 mu apart on the X chromosome of Drosophila. A female of genotype a+ b/a b+ is mated with a wild-type (a+b+/Y). a. What is the probability that one of her sons will be either a+b+ or a b+ in phenotype? b. What is the probability that one of her daughters will be a+b+ in phenotype? 44. Three recessive autosomal mutations in Drosophila: a versus wild-type A. b versus B,...
Please help (2) In Drosophila there are three genes lozenge (z), singed (s), and crossveinless (c),...
Please help
(2) In Drosophila there are three genes lozenge (z), singed (s), and crossveinless (c), with each mutant allele recessive to the wild type allele. A cross between females heterozygous for these three loci and wild-type males yielded the following progeny: Females1010 Males + 39 430 +Cz 32 s27 C+ 441 SCz 31 Using these data, construct a linkage map (4 points) of the 3 genes and calculate the coefficient of coincidence (2 points) and interference (2 points).
2. Three genes and their mutations are found on the third chromosome in fruit fly Drosophila...
2. Three genes and their mutations are found on the third chromosome in fruit fly Drosophila melanogaster. Of these three genes, scarlet eyes (st) are recessive to red eyes (st"), cbony body color (eb) is recessive to gray body color (eb"), and spineless (ss), the st presence of small bristles, is recessive to normal bristles (ss). You eb SS were given a heterozygous fly (st'st eb'eb ss'ss) and were asked to eb ss design an experiment to map the distance...
Mapping genes with recombination frequencies in Drosopna 1. Suppose you know of three linked loci on...
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4. You are studying three genes in corn and performed a three-point cross. The three genes...
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Genetic Linkage The six genes listed below are all located on Chromosome 2 of Drosophila melanogaster....
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Can you please help me with this problem: 3. The allele b gives Drosophila flies a...
Can you please help me with this problem:
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In Drosophila, a fully hetero sophila, a fully heterozygous female with the X-linked recessive genes a...
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Mapping genes with recombination frequencies in Drosophila 1. Suppose you know of three linked loci on the Drosophila X chromosome (a, b, and c). Assume that you are starting out with true-breeding stocks that show all three recessive traits and true-breeding stocks that show all three dominant traits. A. If you wanted to do a 3-point test cross to map the three loci, how would you set up the cross? What genotypes do you use for males and females in...
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43. Genes a and b are X-linked and are located 7 mu apart on the X chromosome of Drosophila. A female of genotype a+ b/a b+ is mated with a wild-type (a+b+/Y). a. What is the probability that one of her sons will be either a+b+ or a b+ in phenotype? b. What is the probability that one of her daughters will be a+b+ in phenotype? 44. Three recessive autosomal mutations in Drosophila: a versus wild-type A. b versus B,...
Please help
(2) In Drosophila there are three genes lozenge (z), singed (s), and crossveinless (c), with each mutant allele recessive to the wild type allele. A cross between females heterozygous for these three loci and wild-type males yielded the following progeny: Females1010 Males + 39 430 +Cz 32 s27 C+ 441 SCz 31 Using these data, construct a linkage map (4 points) of the 3 genes and calculate the coefficient of coincidence (2 points) and interference (2 points).
2. Three genes and their mutations are found on the third chromosome in fruit fly Drosophila melanogaster. Of these three genes, scarlet eyes (st) are recessive to red eyes (st"), cbony body color (eb) is recessive to gray body color (eb"), and spineless (ss), the st presence of small bristles, is recessive to normal bristles (ss). You eb SS were given a heterozygous fly (st'st eb'eb ss'ss) and were asked to eb ss design an experiment to map the distance...
Mapping genes with recombination frequencies in Drosopna 1. Suppose you know of three linked loci on the Drosophila X chromosome (a, b, and c). Assume that you are starting out with true-breeding stocks that show all three recessive traits and true-breeding stocks that show all three dominant traits. A. If you wanted to do a 3-point test cross to map the three loci, how would you set up the cross? What genotypes do you use for males and females in...
4. You are studying three genes in corn and performed a three-point cross. The three genes are green (V) vs Viniscent (V) seedlings, blue (Pr) vs red kernels (pr) and white (B ) or brown (bm) leaf midrib color. The table below list the offspring resulting from a testcross with a female F1 heterozygote. Type of gamete (NR, SCO, DCO Phenotype Progeny Gamete from F1 heterozygote Virescent seedling red 101 kernel Red kernel 175 Red kernel, brown midrib 259 Virescent...
Genetic Linkage The six genes listed below are all located on Chromosome 2 of Drosophila melanogaster. Your goal is to construct a genetic map of Chromosome 2. That is, determine the order of these genes along chromosome 2 and the map distance in centimorgans between each gene. To complete this task, you will be given the results of a variety of two-point test crosses involving these genes. For each test cross you may assume that the female is heterozygous and...
Can you please help me with this problem:
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In Drosophila, a fully hetero sophila, a fully heterozygous female with the X-linked recessive genes a bande not necessarily in that order on the chromosome) was mated to ma c(not necessarily in that order on the chromosom in that order on the chromosome). The offspring occurred in the following phenotypic ratios: Phenotypes Numbers wildtype ac,b 426 428 cb b, a c, a Total 1000 a) What is the arrangement among the genes? Which gene is in the middle? b) What...
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