10. What is a major problem with Friedel-Crafts alkylation? A) It requires high temperatures. B) The...
19. What is the major organic product obtained from the following reaction? Huso A) 1 B) II C III D) IV 20. What is the major organic product obtained from the following reaction? o ca A) I B) II C III D) IV 21. Which of the following substituents are activators in electrophilic aromatic substitution? A) CH30— B) CI— C) NO2 D) HSO3- 22. Which of the following substituents are deactivators in electrophilic aromatic substitution? A) HO– B) CH3NH –...
Draw the major organic product of the following Friedel–Crafts alkylation. (An excess of benzene is present.) aw the major organic product of the following Friedel-Crafts alkylation. (An excess of benzene is present.) AICI, Previous ⓧ Give Up & View Solution # Try Again Next Exit Explanation This reaction is an electrophilic aromatic substitution. The aluminum chloride polarizes the chlorine-carbon bond of the alkyl halide, imparting carbocation character (i.e., electrophilicity) to the alkyl group Since an excess of benzene is present,...
Write a structural formula for the product from Friedel-Crafts alkylation or acylation of benzene for each compound: CI olar a) b) Complete these electrophilic aromatic substitution reactions. Br SOZH heat + H2SO4 b) HNO3 H2SO4 Predict the major product of each electrophilic aromatic substitution OH OH NO2 Br2 b) NO2 SOZ H2SO4 CH3 c) Br2 AICI: SO3H
Friedel - Craft Acylation Synthesis of 4-Methoxiacetophenone Background Information 1.- What is an electrophilic aromatic substitution? 2.- Give three examples of activating groups. Explain why they activate the ring for substitution. 3.- Give three examples of deactivating groups. Explain why they deactivate the ring for substitution. 4.- Describe the difference between a Friedel-Craft alkylation and Acylation. Synthesis of 4-Methoxiacetophenone For this Friedel-Craft acylation we will react Anisole with Acetic Anhydride. Write the mechanism and the structure of the final product....
please help in all sections asap!! In a Clemmensen reduction, an aryl ketone is reduced to an Oaryl aldehyde Caryl alkane aryl carboxylic acid aryl ester aryi anhydride Identify the electrophile for the Friedel-Crafts acylation of benzene. O aluminum tetrachloride anion aluminum chloride acylium ion carbocation carbanion Which of the following criteria is necessary for a nucleophilic aromatic substitution reaction? © A. The ring must contain a very strong electron withdrawing group. B. The ring must contain a leaving group....
please show the mechanism of this reaction C is the correct answer 18. What is the major organic product obtained from the following reaction? (CH3)2C=CH2 H2SO SOGH SO3H A) I B) II C) III D) IV
3. Which of the following is/are false regarding Friedel-Crafts alkylation? H2 gas is a by-product Alkyl halide can rearrange rapidly following heterolysis AlCl3 is the electron-deficient species when generating the reactive electrophile A. I only B. i and i C. li only Frank D. i, ii, and iii are false.
U. Soo-school-bet.cn E. 4-bromo-1-chloro-2-nitrobenzene 10 Identify the aromatic compounds AI and II B. II and 111 D. I. II and II E none of the above C. I and III 11. What is the value of a from Hucke's rule for the following aromatic compound? D. ES G3 12 The Birch reduction of benzene with sodium in NH.CH.Oh goes by a four-step mechanism The first step is the A. transfer of a proton from NH, to benzeme B. transfer of...
help explain how to get products in all questions please!!! What is the product for the following three-step reaction sequence? A) I B) II C) III D) IV E) V What is the major product obtained from the following reaction sequence? A) I B) II C) III D) IV E) V What is the final product, C, obtained via the following sequence? A) I B) II C) III D) IV E) V What is the product for the following three-step...
what exactly am I doing wrong? Draw the major organic product(s) for the following Friedel-Crafts acylation reaction: