Provide the products. leq NaOH Hint: -CX3(X-Cl, Br, I is a good leaving group. 1. LDA(strong...
1. predict the products KOH, H2O + Ph H heat a. (21.4) 1. LDA (strong bulky base) vi H b. 2. then heat H (21.4) c. NaOH/ H2O i i H cold (21.3) 1. LDA ܘܐ 2. e. 3. mild acid for neutralization (21.5) 2. Predict the products NaOCH2CH3 1. NaOH/H2O 2. H HOCH2CH3 Br Br 3. Heat a. Nao in ethanol of b. (C9H1403) 21.8 ol H*, Brz. C. (21.1) NaOH, Bra d. (21.3) PC13, Br2 ОН e. (21.1)
Provide the products for the following reactions: 1. LDA, THF, -78 C 1. LDA, THF, -78 C a yoyo a la misma 0 2. VI NaOCH3, CH3OH 1 eq. 2. H30*. H20
ndyla S Chapter 7 (Snl-Sn2-E1-E2) Revie w +Problems 1°Leaving group (example): Br React with the following reagents (Strong base /strong nucleophile) B) I, NC, Na (Strong nucleophile/ weak base) C) H (NaH or Ca) tBuO/tBuOH (Strong base/non- nucleophile) D) H:0, ROH, RCO2H Weak nucleophile/ very weak base- even acidie "Solvolysis" - type reactions P 2010 2° Leaving group (example): (sometimes "hindered") Ri React with the following reagents (Strong base / strong nucleophile) B) I, NC. N (Strong nucleophile/ weak base)...
Sort the molecules. Strong Base (SB)= stable or unstable good or bad Leaving group Name: Weak Base (WB) = stable or unstable good or bad leaving group Category 1 (A = large e-cloud delocalizes anion): Category 2 (R= resonance stabilized anion): Category 3 (neutral): *Circle any strong bases that are NOT good nucleophiles (why?) Weak acid (WA) (2) Strong acid (pka <O) (SA) Category 1: Category 2: Category 3: If one of these molecules are present do THIS In the...
1. Cl, H20 2. KOBU 1. NaOH, H20 2. PCC 1. ICH Znl, Et, 2. MsCl, pyr 3. LDA 1. HBr, 'BuOOH, hv 2. NaCN, DMF 2. Given both reactants and products, provide correct chemical reagents and solvents to complete the reaction. You might have multiple choices: a. (i) OH + enantiomer CHO CHO
1. Provide the major products for the following reactions. (5) CH3ONa CH3! 1. LDA. -78 deg 2. (CH3)2 Sici @ 2% NaOH CH3OH, heat @ C=0 HCI coEt NaOEVETOH H30*heat Br Br CO,Et
1. What is the tautomer, of the functional group 'ketone', called: - 2. Predict the product(s) of the following reaction and assign the proper equilibrium arrows: :N: H H 3. Label major and minor products. Then explain what causes the major to be the major. Bry, H x & Br Br 4. Draw the aldol product and the aldol condensation product of the following molecule: aldol aldol condensation H 5. What single molecule will make the first molecule? What single...
1. What is the tautomer, of the functional group 'ketone', called: - 2. Predict the product(s) of the following reaction and assign the proper equilibrium arrows: :N: H H 3. Label major and minor products. Then explain what causes the major to be the major. Bry, H x & Br Br 4. Draw the aldol product and the aldol condensation product of the following molecule: aldol aldol condensation H 5. What single molecule will make the first molecule? What single...
2. (1.5 pts) Label the following reagents as Good or Poor Nucleophiles AND as Strong or Weak Bases. OK Na SH 3. (1.5 pt) Predict the productts) of the following reactions, if there are multiple products indicate which, if any, is the major product. Be sure to clearly mark the stereochemistry of chiral carbon atoms and draw multiple products if there is more than one stereoisomer that forms. HCI MeOH H2SO H2 Pd/BaSO4 quinoline 4. (3 pt) For the following...
Help with 1-6 Enols and enolates 1. What is the tautomer, of the functional group 'ketone', called: 2. Predict the product(s) of the following reaction and assign the proper equilibrium arrows: :N: H H 3. Label major and minor products. Then explain what causes the major to be the major. Br,H 4. Draw the aldol product and the aldol condensation product of the following molecule: aldol aldol condensation تل H 5. What single molecule will make the first molecule? What...