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ndyla S Chapter 7 (Snl-Sn2-E1-E2) Revie w +Problems 1°Leaving group (example): Br React with the following reagents (Strong base /strong nucleophile) B) I, NC, Na (Strong nucleophile/ weak base) C) H (NaH or Ca) tBuO/tBuOH (Strong base/non- nucleophile) D) H:0, ROH, RCO2H Weak nucleophile/ very weak base- even acidie Solvolysis - type reactions
P 2010 2° Leaving group (example): (sometimes hindered) Ri React with the following reagents (Strong base / strong nucleophile) B) I, NC. N (Strong nucleophile/ weak base) C) H (NaH or CaH2) tBuo tBuOH (Strong base/non- nucleophile) D) H:0, ROH, RCO2H Weak nucleophile/ very weak base- even acidic Solvolysis - type reactions
Ts 3° Leaving group (example): (always hindered) React with the following reagents (Strong base / strong nucleophile) B) I, NC, N (Strong nucleophile/ weak base) C) H (Nall or Call) tBuO/tBuOH (Strong base /non- nucleophile) D) H:0, ROH, RCO H Weak nucleophile/ very weak base- even acidic Solvolysis - type reactions
locked in Axial leaving group React with the following reagents Mechanism Tvpe(s)? + products (Strong base / strong nucleophile) B) I, NC, N (Strong nucleophile/ weak base) C) H (NaH or CaH2) tBuo/tBuOH (Strong base /non- nucleophile)
locked in Equitorial leaving group React with the following reagents Mechanism Tvnels)2+products) (Strong base/strong nucleophile) B) I, NC, N3 (Strong nucleophile/ weak base) C) H (NaH or CaH2) tBuO/tBuOH (Strong base /non- nucleophile)
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H. 討. RO 시 N2Locked 2nAx X) CN イH(Ty Pe) SN 3 SN CN 3 2 Alkew too ア2 Mechanism 2 R i SN2 R, 2N 2 CL eN A, 04R. OTS SNN E. e. alkene

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