Question

10) Draw a box-and-arrow (SMRF) model representing HOW expression of the sickle-cell allele results in the sickle-cell disease phenotype At a minimum, use the following structures: allele, chromosome, DNA, gene, mRNA, protein, genotype, phenotype. You may include additional structures, or repeat a structure more than once, if it helps you convey the function of the model. Modify your wording to make the model specific to the case of sickle-cell anemia. Remember to label your arrows. (10 points) Remember the conventions for model-building: To create a meaningful model of a biological system, you will need to: 1. represent all structures in boxes and mechanisms (or relationships) on arrows; 2. connect all boxes together within a single model; 3. make sure each arrow has a direction (meaning it is not just a line!) and a label; 4. be able to read each "box-arrow-box" group as a complete, coherent statement; and 5. build the model so that it illustrates the function of the system.

Answer 1