Question

What are siderophores? Giving an example of siderophore from a bacterium, explain the role of siderophore in the pathogenesis and survival of that bacterium.

Answer 1

Answer=

siderophores defination = Siderophores are small, high affinity iron- chelating compounds secreted by microorganisms such as bacteria and fungi and serving to transport iron across cell membranes.

example of siderophore from a bacterium are as follows:

1.antrax pathogen Bacillus anthracis releases two siderophores :bacillibactin and petrobactin.

2. Desferrioxamine B - produced by Streptomyces pilosus and Streptomyces coelicolor

3.enterobactin - produced by Escherichia coli and enteric bacteria

4.Vibribactin - Vibrio Cholerae.

role of siderophore in the pathogenesis and survival of that bacterium as follows:

1.siderophores participate to the mobilization of iron and other elements and are involved in the virulence processes.

2.Siderophores are small molecular iron chelators that are produced by microbes and whose most important function is to sequester iron from the host and provide this essential metal nutrient to microbes.

3.