Question

A4Trait not scored for this generation A. What is the inheritance pattern of this trait? X-linked dominant B. what are the predicted phenotypes for the children A1, A2, A3, and A4? Males unaffected, females both affected and heterozygous for allele giving disease C. You isolate DNA from the Al-A4 generation and amplify the region corresponding to the gene and perform for the A1-A4 children? an EcoRl digestion. Based on the parents' pattern, what do you expect to see Ecoiki

Note: The answers are stated. I need the explanation for why C is as depicted.

Please thoroughly explain why C is as given. Thank you.

Answer 1

In the given case, the inheritance pattern is X-linked dominant, which means the dominant gene is carried by the X-chromosome. Therefore, if a male is affected by this type of inheritance, then his all daughter would be affected because each of his daughters will carry an XX sex chromosome, one each from father and the mother, and since X chromosome of the father is dominant, so the daughters will certainly be affected. so their corresponding gene would more like to resembles like of their father. on the other hand, sons will not carry an X chromosome from their father, rather they would carry a Y-chromosome. therefore, their corresponding genes would not show similarity. hence, the given answer is as.