Epigenetic is the study of changes in gene expression which does not changes the sequence of the gene. These changes are heritable. So there is two type of most often gene-associated markers.
1. Chemical ( eg DNA Methylation)
2. Protein ( eg Histone modification)
Due to the plasticity of DNA methylation, it is reversible most of the time but In females, random X-chromosome inactivation is initiated during gastrulation in the epiblast through the X-inactive specific transcript (Xist) gene, which encodes a long non-coding RNA that silences the X-chromosome. In human females, this is also known as a Bar Body.
Which epigenetic mark is most often associated with genes that are inactive for the lifetime of...
Most eukaryotic genes are normally inactive and require positive regulation. Determine whether the situations described are associated with positive regulation (activation) or negative regulation of eukaryotic genes. If one of the choices is not a factor involved in regulating transcription or if a choice does not apply, identify it as "neither."
Which of the following represent epigenetic changes caused by a pathogen that can affect its ability to cause infection in the host? Check all that apply Activation or inactivation of host cell DNA Binding to RNAs that silence genes ロロロロロ Affect host cell DNA that is responsible for cytoskeleton organization Exchange of capsule genes between pathogen and host cell Secretion of endotoxin from the cell wall of a pathogen
Are there specific genes associated with Type I diabetes? If so, which specific genes are associated with which ethnicities? I found that the HLA genes on chromosome 6 increase the risk of getting type 2 diabetes but was having a little more trouble with the second part of the question.
Repin ma regions associated with a trait by GWAS are often nS containing no transcribed/translated genes, because 3- they are centromeric. they encode transcription factors they contain no DNA. there are only about 25,000 genes. e. they are probably Neanderthal DNA remnants.
Which of the following is a false statements about tumor suppressor genes? Gene amplification (duplication) of a tumor suppressor gene is less likely to result in cancer than gene amplification of a proto-onocogene. Individuals with a single normal copy of a tumor suppressor gene are more prone to cancer than those with two normal copies. Inactivation of tumor suppressor genes can lead to enhanced cell survival and cell proliferation. Epigenetic changes that silence tumor suppressor genes would not lead to...
Which is not an example of an epigenetic process? genomic imprinting independent assortment of alleles X inactivation direction of DNA methylation by siRNAs cell differentiation
Some genes in plant cell nuclei are most similar to genes from cyanobacteria. This is explained by: a)horizontal transfer of endosymbiont genes to the nucleus. b)plants and cyanobacteria having a common ancestor. c)horizontal gene transfer from non-photosynthetic bacteria to plant nuclei.
Cancer biologists have focused on proteins/genes associated with the "restriction point" of the cell cycle to develop the next generation of chemotherapeutics. What is the "restriction point"? Name at least 3 conditions that need to be met for a cell to move beyond the restriction point.
1) Which of the following conditions is most likely to cause the lactose operon to be transcribed? A) There is more glucose in the cell than lactose. B) There is glucose but no lactose in the cell. C) The cyclic AMP and lactose levels are both high within the cell. D) The CAMP level is high and the lactose level is low. 2) How does the transcription of structural genes in an inducible operon occur? A) It occurs continuously in...
A mutation in a steroid hormone receptor that renders it completely inactive will have which of the following effects? A. Inhibit transcription of genes controlled by the steroid hormone. B. Recruit RNA polymerase to its promoter and activate transcription. C. Increase binding of the receptor-hormone complex to the steroid hormone response element. D. Increase the affinity of the steroid hormone to the receptor.