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1 The data in table 1 below are measurements from a group of 10 normal males and 11 males with left-heart disease taken at au

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Answer #1

GIVEN:

The data on total heart weight from a group of 10 normal males and 11 males with left heart disease:

THW of Left heart disease males THW of Normal males
452 312
755 364
331 349
499 286
301 312
450 277
469 303
375 348
310 400
592 277
424

The given problem is to test whether the means of total heart weight between normal and left heart diseased males is same or not. Thus we use "Two sample t test with unequal variance" to test this claim.

HYPOTHESIS:

HO: M1 – M2 = 0 (That is, there is no significant difference in mean total heart weight between normal and left heart diseased males)

0 7 11 – 17:17 (That is, there is significant difference in mean total heart weight between normal and left heart diseased males)

LEVEL OF SIGNIFICANCE: g= 0,05

TEST STATISTIC:

t = [(-11-22)]/(si/nı) + (s/n2)

which follows t distribution with degrees of freedom given by,

df = [(st/n1) +($}/n2)]/[(s/nı)?/(n1 – 1)] + [(8/12)/(n2 – 1))

CALCULATION:

I have used excel function to calculate mean and standard deviation of two samples.

Mean: "=AVERAGE(select array of data values)"

Standard deviation: "=STDEV(select array of data values)"

Sample size of left heart diseased males (ni) = 11

Sample size of normal males (n2) = 10

Sample mean heart weight of left heart diseased males (21) = 450.73

Sample mean heart weight of normal males (T2) = 322.8

Sample standard deviation of left heart diseased males (si) = 133.496

Sample standard deviation of normal males (S2) = 41.033

DEGREES OF FREEDOM:

df = [(st/n1) + ($}/n2)]/[[{s} /nı)?/(n1 – 1)] + [(8/12)?/(n2 – 1)]]

  = [(133.4962/11)+(41.033/10)] /[[(133.4962/11)/(11-1)]+[(41.033/10)/(10– 1)]]

=3198654.14632/262474.81+3149.855

df = 12.042 12

TEST STATISTIC:

t = [(-11-22)]/(si/nı) + (s/n2)

= [450.73 – 322.8]/ (133.4962/11) + (41.0332/10)

= 127.93/42.2904

t = 3,03

P VALUE:

The two tailed p value for test statistic t = 3,03 with 12 degrees of freedom is,

2 * Plt > 3.031 = 2 * Plt >3.03]

= 2*(1 – Pſt <3.031)

=2+1-0.9948)

=?*0,0052

= 0.0105

The p value is 0.0105 .

DECISION RULE:

Reject H, if pualue <a

CONCLUSION:

Since the calculated p value (0.0105) is less than the significance level g= 0,05 , we reject the null hypothesis and conclude that there is significant difference in mean total heart weight between normal and left heart diseased males.

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