None of the four Options won't give our product. In option 4 instead of EtMgBr, if we have used MeMgBr we will get the product as shown below.
Option 1 and option 3 are same. In it, H20 in 4th step will lead to an alcohol(not our product).
Option 2 H3O+ in step one will be acted nowhere in the molecule. And even if it is able to remove Cl- from the molecule, the final product will be a alcohol.
So we are left with option 4(with modification: replacing Et by Me in EtMgBr.
Please include an explanation Choose a plausible synthesis for the following transformation, from the options below....
Which of the following is an efficient synthesis for the transformation below? CI 1) NaOH 2) РСС, СН2CI2 3) EtMgBr 4) Na2Cr207, H2SO4, H20 1) Hзо+ 2) PCC, CH2Cl2 3) MeMgBr 4) Hа0 5) Na2Cr207, H2SO4, H20 1) NaOH 2) РСС, СH2CI2 3) MeMgBr 4) H20 5) NaBH4, MeОн 1) NaOH 2) РСС, CH2CI2 3) MeMgBr 4) H20 5) Na2Cr207, H2SO4, H20 Which of the following is an efficient synthesis for the transformation below? H 1) LIAIH4 2) H20 3)...
Integrated Problem 12.54d X Incorrect. Propose an efficient synthesis for the following transformation: vi CI The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. A B с t-BuOK 1) MeMgBr; 2) H20+ Na2Cr207, H2SO4, H20 NaOH D F G H E...
If someone can help please help me with this, and please show each reaction so I can learn! 6: 3: Reaction of 2-propanol with the reagents listed here afforded which product? 1) PBr3 2) Mg, Et20; 3) CHsCHO; 4) H20; 5) PCC, CH2Cl2; 6) [H3O], Br2; 7) Pyridine 8) Et2CULI 9) C3 10) NaOH, Br2; 11) H3O 12) SOCI2;13) LİAİ(OR)3H 14) H20; 7: Reaction of oxirane with the reagents listed here afforded which product? 1) MeMgBr; 2) H20; 3) PCC,...
Propose an efficient synthesis for the transformation below. Enter the appropriate number of letter from the reagent list handout Step 1 Step 2 Step 3 OH Alkyl Halides (X = CI, Br or 1) and Acyl chlorides: Assume Allig 15 present, if needed CIP CU CH3X X CI E A B EE Ketones. Aldehydes and Epoxides: Assume "then H20" is included if a protonation step is needed F A A K 0 MN Р Grignard, Wittig and Organocuprate Reagents: Assume...
Question 23 Identify the reagents that you would need to accomplish each of the following transformations. 12.24a a ai 1) Na2Cr2O7, H2S07, H2O 2) xs EtMgBr 3) H2O 1) EtMgBr 2) H20 3) Na Cry07, H2SO4 H20 1) EtMgBr 2) H20 1) MeMgBr 2) H2O 3) Na2Cr2Oy, H2SO4, H2O
7. Please choose the set of reagents that will accomplish the following transformation with the highest yield od-dhe CH (A) (B) | 1) HOẶC, Bra 1) H30*, Br2 1) NH(Me)2, cat. H2SO4 2) Mel (D) 1) NaOH, Bra 2) Mgº, THE 3) Mel 2) pyridine 2) pyridine 3) Me2Culi 3) MeMgBr
Propose an efficient synthesis for the transformation below, using two sequential reductive aminations. Enter the appropriate number or letter from the reagent list handout. Propose an efficient synthesis for the transformation below, using two sequential reductive aminations. Enter the appropriate number or letter from the reagent list handout. Step 1 + NaBH3CN, H+, Step 2 - NaBH3CN, H+ Reagent List (Updated 4/30/2020) Enter # or letter in the appropriate boxes. Note: Exam responses are case insensitive Alkyl Halides (X = Cl,...
Identify the reagents necessary to accomplish the following transformations: Choose from the following list of reagents: 1) xẼ NaNH, 2) H20 10 g-BBN 2) H2O2, NaOH 1) ELMgBr 2) H2O 1) Hg(OAC)2, H20 2) NaBH4 1) TSCI, pyridine 2] -B40k 1) MeMgBr 2) H20 Brz 1) t-BuOK 2) TSCI, pyridine TSCI, pyridine Na2Cr2071) NaBH4 H2SO4, H20 20 H2O2, NaOH PCC, CH2Cl2 Enter the correct letter for each step of the reaction in the boxes below. (Reagents can be used more...
Problem 10.57 ropose a plausible synthesis for the following transformations. Choose from reagents (A-H): B. 1) NaNH2 2) Mel 3) 9-BBN 4) H202, NaOH 1) Br2 2) Excess NaNH2 3) H20 1) Br2 2) Excess NaNH2 3) H20 4) H2S04. H20, HgSO 1) NaNHz 2) EtI 3) Na, NHa () 1) Excess NaNH2 2) H20 3) NaNH2 4) Mel 5) Na, NH3 C) 1) NaNH2 2) 3) H2, Pt 1) 9-BBN 2) H202, NaOH 1) Excess NaNH2 2) H20 3)...
Question 9 Which one of the following reaction steps work best to carry out the transformation shown below? ? ? H 1) BH3, THF PCC A) 2) H2O2, NaOH CH2Cl2 H20, H2SO4 (cat.) PCC B) CH2Cl2 1) BH3, THF HIO1 C) 2) HOh, NaOH D) OsO4 (CH3)3COOH, OH K2Cr207, H2SO4 H2O С в СА D