Question

1. Of these cellular targets of antimicrobials, drugs designed against which target are likely to have the least selective toxicity? Ribosomes Cell membrane O Cell wall Nucleic acid synthesis 2. Which of these antimicrobials has the broadest spectrum of activity? Cephalosporin Polymyxitn Tetracycline 3. Your microbilome is most susceptible to changes when takinga s spectrum antimicrobial O selective O narrovw broad . Which microbial group is the easiest to selectively target with antimicrobials? Bacteria Viruses Fung Helminths 5. Based on Kirby-Bauer testing, a microbe is determined to be susceptible to both antiblotic X and antibiotic Y. Further testing indicates that antibiotic X has a therapeutic index the best choice based on the Information given? Antibiotic Antiblotic Y Either one would be an equally good choice based on the information given. Prey 10" " Next

Answer 1

Answer 1. The correct option is D. Nucleic acid synthesis. This will have least selective toxicity against the pathogen because it will also effect the nucleic acid synthesis of the host also, amd thus will be cytotoxic to host as well.

Answer 2. The correct option is D. Tetracycline. Tetracycline is a highly effective broad spectrum antibiotic.

Answer 3. The correct option is C. Broad.

Answer 4. The correct option is A. Bacteria.

Answer 5. The correct option is A. Antibiotic X. A higher therapeutic index is preferred for better safety profile. The higher the therapeutic index the less toxic it is for the host.