Question

1.) Which antibiotic target could have the most toxicity associated with it?

A. 50 S ribosomal subunit

B. folic acid synthesis metabolic pathway

C. cell wall

D. cell membrane

2.) You are hoping to discover a new antimicrobial drug that targets fungi. Which structure might you hope to have your antimicrobial target to minimize toxicity?

A. ribosomes

B. chitin

C. peptidoglycan

D. phospholipids of plasma membrane

3.) An antiviral drug that blocks the activity of the enzyme integrase is used to treat which disease?

A. Malaria

B. Influenza

C. HIV

D. Herpes

4.) Which of the following is NOT a mechanism by which bacteria resist antibiotics?

A. efflux pump

B. modification of the antibiotic

5.) the lowest concentration of an antibiotic that prevents all growth is known as:

A. minimum inhibitory concentration

B. maximum inhibitory concentration

C. Kirby-Bauer disk diffusion assay

D. CRE

Answer 1

Answers:

Hi, as per Chegg Rules, we have to answer the first question only foe the multiple questions. But here too many questions, so here I answer all the question and give the explanation for the first question only.

1) D. Cell Membrane

Explanation: Because of the presence of the additional protection afforded by the outer membrane of gram negative bacteria it tends to be more resistant to antimicrobial agents than Gram-positive bacteria. Gram-negative bacteria have an outer membrane rich in lipo polysaccharide, antimicrobial peptides can bind to the outer membrane of Gram-negative bacteria and block passage of solutes between the periplasm and the cell exterior, resulting in bacterial toxicity.By considering this as an example we can say that the cell membrane has more toxicity associated with it.

2) B. Chitin

3) C. HIV

4) B. Modification of the antibiotic

5) A. Minimum inhibitory concentration

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