Give mechanism? OTMS 9% OCH3 5mol %-78°C TMSOTF 91% yield, 1:1.4 syranf
Give the FULL mechanism for the synthesis of the product
1) BuLi, Et20,- 78 → .45 °C, 1 h 2) > Et20 TBSO / -78 .25 °C. 5 h 151 SS HMPA/E20, - 780°C OTBS -NHTS OTBS 152 TBS 56 % 150 153 Raney Ni EtOH, H2, r.t 69 % 155 154
1. A. Predict the products for the following reaction and write a rational mechanism. OCH3 (CH3CO20 AICI: Mechanism: 1. B. Why are much larger quantities of aluminum chloride required for Friedel-Crafts acylation reactions than for alkylation reactions? T.C. A student reacted anisole with acetic anhydride in dichloromethane using aluminum chloride as a catalyst. The student used the experimental procedure as described in the laboratory manual. At the end of the experiment the student failed to get +- methoxyacetophenone. Give reasons...
Mechanism for this reaction
Na NH3 liquid, -78°C
How do you do the mechanism for (e) and what is the
final product?
c. Cl d. (1) excess CH2Mgl CI (2) H 0+ e. (1) DIBAL-H (-78 °C) (2) H20→ OCH3 (1) DIBAL-H (-78 °C) (2) H20 ntheses of Ketones and Aldehydes 0:52 PM
describe how the actual yield ( 1.48) compare to theoretical yield ( 1. 78 ) using the percent yield.
Give the correct organic product for the following reaction at
�78 �C:
Give the correct organic product for the following reaction at - 78 degree C: 1. DIBAL - H hexane 2. H2O
4. When 10 g of benzene (Molar mass 78 g/mol) reacts with 9 mL of concentrated HNO3 (16 M) and 9 mL of H2SO4 (18 M), 8.1 g of nitrobenzene (molar mass 123 g/mol) and 1.2 g of an unknown compound with a high boiling point are obtained. a. Identify the limiting reagent. b. Calculate the percent yield of nitrobenzene. c. Give the name and structure of the most probable side product with the high melting point. d. Explain, with...
show the detailed mechanism for the following reaction.
Hac 1) DIBAH, Toluene, -78°C 2) H+, H,0 LHC40 + NH, N
1. Give the major product(s) for the following reactions. HNO3 H,so, a) OCH3 он HNO3 H2SO4 OH он b) NO HNO3 H2SO4 C)
7) Give the mechanism including the transition state. сн.ct çı SN2 НН 8) Give the mechanism. CH1 보 SN1 CHCH,CH-C CH. но H Br 9) Give the mechanism of the reaction shown below. CH CI E1 CH,OH 10) When 1-bromo-2,2-dimethylcyclopentane is heated in ethanol, one of the products which results is shown below. Provide a detailed, stepwise mechanism for the production of this compound, and give the name of the mechanism by which it is produced. CH3 CH3