9. Given the following pedigrees which is autosomal dominant, autosomal recessive, x- linked dominant, x-linked recessive?...

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9. Given the following pedigrees which is autosomal dominant, autosomal recessive, x- linked dominant, x-linked recessive? A)

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Answer 1

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A. Autosomal Recessive disorder

Skipping in generation shows it is recessive disorder.

If it is X linked disorder II 1 XAY and II-2 XAXa. So no females is affected. But here female also affected confirms it is not X linked but autosomal recessive disorder.

B. X-linked Recessive disorder

Skipping in generation shows it is recessive disorder.

If it is X linked disorder II 1 XAY and II-2 XAXa. So no females are affected and half of males are affected. Here also it confirms no females are affected only males are affected so it is X linked recessive disorder.

C. Autosomal Dominant disorder

No skipping in generation so it is dominant.

If it is X linked Dominant disorder means - males affected all females as to affected. But here males are affected I-4 XAY and I-3 XaXa. So all female as to affected but here one female is not affected in offspring. So it is Autosomal.

D. X linked DOminant disorder.

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