Question

The MyoD transcriptional regulator is normally found in differentiating muscle cells and participates in the transcription of genes that produse fic proteins, such as those needed in contractile tissue. Amazingly. expression of MyoD in fibroblasts causes these cells n connective tissue to produce proteins normally only seen in muscles. However, some other cell types do not transcribe muscle-specific genes when MyoD is expressed in them. Which of the following statements below is the best explanation of why MyoD can cause fibroblasts to express muscle-specific genes? Unlke some other cell types, muscle-specific genes are still active in fibroblasts The muscle-specific genes must be in heterochromatin in fibroblasts Fibroblasts have accumulated some transcriptional regulators inew genes) during development. O The transcriptional activators belong to a positively regulated operon

Answer 1

TC) Fibroblasts have accumulated some branscriptional regulators) L (new genes) during development . Thus, Fibotast are able to expressen muste-specific genes when Myo D is expressed in them wheres not others because they have not accumulated these transcriptional regulators in common with differentiating muscle cells.

Felt great to answer. Good luck!