Question

Exhibit 17-3 To answer questions 6-10, consider the scheme below where each labeled box corresponds to the question: Refer to Exhibit 17-3. The best reagents for accomplishing transformation 10 are: a. 1. CH3Li, 2. H₃0+ b. 1. Base, 2. CH31 c. 1. RCO3H d. 1. Hz0+ o 's

Answer 1

Answer with explanation is given below :

al. CH₂ Li 2. H₂o0 Tal. Base 1 2. CH ₂ I [c. 1. RCO3H pel Rosa оси no OH Mc Explanation coi the mechemin nism (6). Carbonyl carbon acts as an electrophile and methy) group in CH₂ Li acts as nucleophile, since, carbon atom of methyl group b. is is more electronegative than Lithiums atom, so carbon is partial negatively charged and Lithium is partial posittely charged S. s ub- n LOOL; Oē OH orang yang cil. Chl31

with H₂00 to give Alcoholic elimination group (OH) reacts product a OH Ononium ion + H₂O Alcoholic group (-OH) reacts with Bare to form an anion which acts as a nucleophile, and it undergoes nucleophilic substitution reaction as tease K Base مد مدت کی bol. Base HCTLO 13 Anion (Nucleophile) AIL Alkenes i undergo eponication reaction with peracids (RCOOOH). Bugun, Terence II OTO +R600M

(10). 04 ns E pomides undergo acidic hydrolysis to give . trans diol since eponide is formed below the sing , so water (H2O) approach from abou sina as shown below :- sing, as Pillot Theron dol. H3O_ (10.) - , 0 TIILIOH ooh OH