A young couple is planning to have children. Knowing that there have been a substantial number of stillbirths, miscarriages, and fertility problems on the husband’s side of the family, they see a genetic counselor. A chromosome analysis reveals that, whereas the woman has a normal karyotype, the man possesses only 45 chromosomes and is a carrier of a Robertsonian translocation between chromosomes 22 and 13.
a. List all the different types of gametes that might be produced by the man.
b. What types of zygotes will develop when each of the gametes produced by the man fuse with a normal gamete produced by the woman?
c. If trisomies and monosomies of chromosomes 13 and 22 are lethal, what proportion of the surviving offspring will be carriers of the translocation?
A young couple is planning to have children. Knowing that there have been a substantial number...