Propose an efficient and elegant synthesis of each of the following molecules using either diethyl malonate...
Propose an efficient and elegant synthesis of the molecule using only a benzene as your starting material. You may use any alkyl halide or alcohol as your other sources of carbon (excluding HCOCl), and any other reagent you deem necessary. OH Cl
17 April 2019 Problems te wing molecules using either diethyl malonate or alkyl halide or alcohol as your other sources of ny CH3 2. CH3 HaC CH
4. Using either diethyl malonate or ethyl acetoacetate, design a synthesis for the following products: a) b)
Extra Credit Propose an elegant and efficient synthesis of the molecule show below. You may use alcohols of 4 carbons or less as your only source of carbon. H3C CH3 HBr CHs
Propose a synthesis of the following derivative of diethyl malonate using reagents from the choices provided below. (From the choices provided, list the reagent(s) in order that will accomplish this transformation. No more than 4 steps are required. List your answer as a single letter (single-step transformation) or a series of letters (multi-step transformation) with no commas separating them.) Reagents available a. Eto Na g. CH2=CHCH=CHCH,Br b. CH3 CH2Br c. CH3 CH, CH, CH(CH3)Br d. (CH3)2 CHCH, CH,Br e. CH3...
How would you synthesize each of the following from either ethyl acetoacetate or diethyl malonate? Show retrosynthesis and forward synthesis|. a) b)
2. Propose an elegant synthesis of the following molecule starting from terminal alkyne compounds of five carbons or fewer as your only source of carbon. You may use any other reagent necessary. CH3 CH3 H3C CH3
(3) Propose an efficient synthesis of target molecules (a) and (b). All of the carbons in the targets must come from one of the compounds below. Draw the structure of the product formed after each synthetic step. Do not write mechanisms. Note Points off for long, inefficient syntheses Нас CH3I OEt OEt H-C CH methyl iodide ethyl 2-butenoate ethyl acetoacetate he ptane-2,6-dione H2C он CH
Extra Credit Propose an elegant and efficient synthesis of the following amine using benzene and alcohols of 4 carbons or less as your only source of carbon
8. Give a synthesis of the compound shown starting from either diethyl malonate (DEM) or ethyl acetoacetate (EAA) shown in the box below. Give all reagents necessary. State clearly whether your starting compound is DEM or EAA. You do not need to draw the intermediate steps. 17 pts] Eto Et Hoce DEM ΕΑΑ. 9. Draw the uncharged product of this synthetic sequence. [4 pts] 1. KOH OCH 3. NaOH(aq) excess 10. By how much will the mass of this compound...