Question

Question 4 (1 point) Saved Which of the following is used in gene recombination of BCR subunits AND gene recombination of TCR subunits? O a) Rag1/2 Ob) RSS Oc) TUT d) All of the above. Question 5 (1 point) Saved Thymocytes undergoing B-selection express which of the following? a) pre-T Ob) CD4 O CDB

Answer 1

Ans- Rag 1/2

Rag 1/2 are recombination activating gene that plays major role in the rearrangement and recombination of the gene that regulate B cell and T cell receptor molecule. They plate role in separation, shuffling and rejoining of VDJ gene

Ans- a) pre-T aplha

Thymocytes during beta selection are double negative cell which means it lacks CD4 and CD8. During beta selection the cell that have successfully expressed the TCR beta chain along with pre- T alpha are selected. The complex thus for pre TCR