Homework Answers
Answer: Complement is involved in lysis
IgG and /or IgM is involved
Type 2 reactions may occur if mismatched blood is given as a transfusion
Cytotoxic T cells play an important role in cytolysis in Type 2 reactions.
Explanation:
Type 2 hypersensitivity reaction is also known as complement dependent reaction in which the antibody directly binds to the antigen on circulating blood cells or on extracellular membrane resulting in Ag-Ab complex. This complex activates the complement, leading to cell lysis.
The reaction takes minutes to hours and is mediated by IgM and IgG, which binds to the antigen on the cells.
Type 2 reactions are seen in blood transfusion reactions, the RBC may enter from one person to another either by blood transfusion or during pregnancy. The RBCs may appear foreign to the antigen that is found on another person’s RBC.
Type I Hypersensitivity reaction involves the production and binding of IgE antibodies to mast cells and basophils containing histamine granules, which is released in this reaction and cause inflammation.
Type 2 reactions are mediated when cell surface antigen are presented to T cells.
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Match each description or example with the correct type of hypersensitivity. Type I (acute) hypersensitivity Type II (cytotoxic) hypersensitivity Type III (immune complex) hypersensitivity Type IV (delayed) hypersensitivity Answer Bank Antigens bind to IgE on basophils and mast cells and stimulate them to secrete vasoactive substances. IgG or IgM binds to an antigen, which leads to lysis or opsonization of target cell. T cells elicit a response 12-72 hours after initial exposure. Anaphylactic shock is an example of this type...
Please match the description to the type of hypersensitivity. 1. acute reaction to an allergen mediated by IgE, mast cells, basophils, and histamine (Click to select) 2. a reaction mediated by T cells and the effector cells enlisted by them. Generally, this reaction takes a day or two to develop after exposure to the provoking antigen (Click to select) 3. mediated by IgG antibody-antigen complexes, which are deposited in basement membranes of some organs and invoke an inflammatory response (Click...
A 48-year-old male patient arrives at the hospital after being rescued from a car accident in which he suffered a serious hemorrhage. He needs a blood transfusion to stabilize. Blood typing test discovers he is A+, Which of the following blood types can he receive? Check all that apply. Check All That Apply A+ and A- B+ and B- AB+ and AB- O+ and O- Please match the description to the type of hypersensitivity. 1. acute reaction to an allergen...
Please categorlze the statements according to the type of hypersensitivity. Contact dermatitis Hives Туре ! Туре ! Туре II Турe IV Mediated by Causes skin wheals and flares histamine Disseminated intravascular coagulation Involves dendritic cells Transfusion Serum sickness reactions Mediated by neutrophil enzymes Involves basophils and mast cells Tuberculin reaction Shock Causes arthus reaction in skin Causes skin inflammation Mediated by T cell cytokines Hemolytic disease of the newbom Causes no skin reactions Mediated by ADCC Reset Next > 15...
Select the statements that apply to hemolytic disease of the newborn. Check all that apply. Check All That Apply This occurs due to Rh incompatibility between an Rh+ mom and Rh- baby. Fetal RBC leakage sensitizes the mother to make anti-Rh antibodies. Anti-Rh antibodies that are lgG can cross the placenta and induce complement-mediated lysis of fetal RBCs. After sensitization with Rh+ fetal RBCs, all subsequent pregnancies (Rh+ and Rh- fetuses) are at risk for hemolytic disease. Hemolytic disease is...
the
components of the DNA include a phosphate molecule
1. Tissue injury occurs. 2. Cellular damage and mast cells which are found in all tissues of the body, release 3. Histamine causes blood vessels to dilatt 4. Dilation of blood vessels causes an incrasc 5. Dilation of blood vessels also increases capillary cellular components of the blood to enter the extracellular space. 6. The first line of defense is the white blood cells known asDeutrophi S 7. Fluid leaves the...
immunology
practing samples and not sure if my answers correct.
1. NK cells are effective against viral infections because many virus infected cells a. are susceptible to lysis b. are susceptible to phagocytosis c. show reduced levels of MHC class I molecules d. show reduced levels of MHC class II molecules e. none of the above 2. Arachidonic acid serves as a substrate in the lipoxygenase and cyclooxygenase pathways resulting in the production of a. histamine, leukotrienes b. leukotrienes, prostaglandins...
12. Antimicrobials may a. produce allergic reactions b. produce toxic effects not only to the microbe but to the hoat c. kill bacteria in our bodies all the above 13. All of the following pertain to the role ofactivated helper T cells in cellular mediatesd immunity except a. differentiation into memory Th cells b. recognize MHC with antigenic peptide on macrophages c. activate Te cells indirectly lead to cytolysis through complement e. indirectl y lead to phagocytosis of large microorganisms...
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