Question

20. Inhibition of the enzyme malate dehydrogenase (MDH) from Plasmodium falciparum is a potential novel treatment for malaria. MDH catalyzes the conversion of malate to oxaloacetate. Which metabolic pathway in P. falciparum will be directly affected if MDH is inhibited? a. Glycolysis b. The electron transport chain c. The citric acid cycle d. Alcohol fermentation 21. Which of the following compounds has the greatest amount of energy for a cell? a. CO b. ATP C. Glucose d. Lactic acid e. NADH 22. Escherichia coli is a facultative anaerobe. Imagine that two cultures of E. coli have been growing in glucose broth for 1 day. One culture was grown with Oz and the other was grown without 02. Which culture, if any, used more glucose? a. The culture grown with Oz used more glucose b. The culture grown without O, used more glucose c. Both cultures used an equal amount of glucose 23. Numerical answer: Not every organism can create 38 ATP from a single molecule of glucose. Organisms that carry out anaerobic respiration and use molecules other than oxygen for respiration are usually less efficient than aerobes. If an organism made 2 ATP per NADH and 1.5 ATP per FADH, how much ATP would this organism make from one molecule of glucose? 24. The explosive TNT (trinitrotoluene) is easily handled by people who use it. For example, it can be melted in a frying pan without it exploding. To cause TNT to explode, a smaller detonation must occur usually through the use of a percussion or blasting cap. Another explosive, Nitrogen Triiodide is much more dangerous to handle. Nitrogen triiodide is a contact explosive, and will detonate if it is simply dropped onto a surface from a height of a few feet. The reason why TNT is more stable than nitrogen triiodide is because: a. TNT has a higher activation energy compared to nitrogen triiodide b. TNT has a lower activation energy compared to nitrogen triiodide CTNT has more chemical potential energy than nitrogen trijodide d. TNT has less chemical potential energy compared to nitrogen triiodide