Question

Consider a typical Sgi pathway involving the reaction of 2-bromo-2-methylpropane with hydroxide as shown below. CH HC-C-Br -N
CH; CH; CH; НО С-.--В сох с — Br HẠC CH А HẠC CHỦ B HỌC CHỦ с CH, CH; CH; НО- НО. -cs Н;С сн; Н;С сн D HẠC CHỜ F E а. А b.B с
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Answer #1

Answer: option B is the intermediate for number 2 position in energy profile diagram.CH3 Solution - (Hz-C-Br + NaOH SNs сиз Reaction approach - СН3 СН3 + сна Си-с- 3 9 CH3 1 З 1 C+ Cr3 Сиз — Сиз СИЗ (1) (2] С

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