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An occupational hazard research company conducted a retrospective cohort study on the relationship between asbestos exposure...

An occupational hazard research company conducted a retrospective cohort study on the relationship between asbestos exposure and mesothelioma in plumbers. There were two study groups — plumbers exposed to asbestos and plumbers not exposed to asbestos. An equal proportion (5%) of study participants in each group was misclassified. i.e. 5% of those exposed were misclassified as non-exposed and 5% of non-exposed were misclassified as exposed. Which of the following statements are true?

  1. The study results will underestimate the association.
  2. The actual association will be stronger than shown by the results.
  3. The study results will overestimate the association.
  4. The study results will be biassed towards the null.
  5. None of the above
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Answer #1

Due to this misclassification, we will that the association value between asbestos exposure and mesothelioma will come down. Hence, our answer is: The study results will underestimate the association.

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