Nigrostriatal dopamine pathway’s unintentional blockage can lead to unpleasant motor side effects which are usually observed in the patients was suffering from schizophrenia and are being treated with antipsychotic medicines and they experience extrapyramidal motor system and tardive dyskinesia as a result. The blockage in these pathways can lead to mota disabilities.
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When treating patients with schizophrenia with antipsychotic medication, sometimes extrapyramidal motor symptoms and tardive dyskinesia result....
Question 2 2 pts When treating patients with schizophrenia with antipsychotic medication, sometimes extrapyramidal motor symptoms and tardive dyskinesia result. Which dopamine pathway is unintentionally blocked to cause these unpleasant motor side effects? Nigrostriatal (Substantia nigra to basal ganglia) Tuberohypophyseal (Hypothalamus to pituitary gland) O Mesolimbic (VTA to nucleus accumbens) Mesocortical (VTA to prefrontal cortex) Question 3 2 pts In a longitudinal study, it was found that adults diagnosed with schizophrenia were MOST LIKELY to experience decreased loss of gray...
L- DOPA, a treatment given to Parkinsons patients, can produce dyskinesia a negative side effect involving tics or uncontrollable movement patterns, cause 1) L-DOPA activates the indirect pathway of the basal Ganglia. 2) L-DOPA is converted into dopamine in the substantia Nigra. Substancia Nigra neurons then project down the spinal cord and excite alpha motor neuron pools. 3)L-DOPA crosses the low brain barrier (BBB) and travels to the primary motor cortex activating random muscle groups. 4) L-DOPA is taken up...