1) Yes this is true, this phenomenon is called allelic exclusion. Only one allele for a heavy chain and one allele for a light chain. The other alleles are not transcribed.
Answer True.
2) A non productive allele of VDJ recombination is an allele which produces an antigen non-reactive antibody.
A self antigen will not bind to any foreign antigens, therefore it is a non- productive allele
A non 3 multiple will cause a frame shift shifting the entire frame of the transcript producing a defunct allele. This is because codons are 3 nucleotides. This is the same reason why multiples of 3 additions wont do as much damage.
The stop codons will also stop transcription.
Therefore the answer is Option 2,3,4
Question 5 3 p Although each B cell carries two alleles encoding the lg heavy chain...
please answer all 4 questions :) Question 7 3 pts Which of the following occur in both B cells and T cells? o isotype switching O somatic recombination o alternative splicing to produce different isoforms of the receptor o alternative splicing to produce a secreted form of the receptor o somatic hypermutation Question 8 3 pts Multiple factors that increase antigen receptor diversity also increase formation of non- productive alleles. Which of the following would generate a non-productive allele? Select...
Which of the following statements is (are) true of a T cell that expresses two α chains (and thus two different T-cell receptors) as a result of ineffective allelic exclusion of the α chain during rearrangement? There will be two unique TCRs on the surface of this T cell. Engaging either of the T-cell receptors on MHC molecules of the thymic epithelium will result in positive selection. If either T-cell receptor binds strongly to self-peptide presented by self-MHC molecules, the...