Homework Answers
Correct answer is option d- Adenylyl cyclase
Explanation: Raf, Atk and Erk are activated by Receptor tyrosine kinases. But adenylyl cyclase is activated by G protein coupled receptor (GPCR). When suitable ligand bind to G protein coupled receptor, the G protein, which remain associated in the cytosolic domain of GPCR, became activated and bound GTP is replaced by GTP. As a result G protein became activated and G-alpha subunit get detached from the beta-gamma subunit of G protein. G-alpha subunit of G protein with bound GTP activates adenylyl cyclase which then converts ATP to cAMP. Then cAMP acts as second messenger and it regulates downstream pathway. So correct answer is option d - adenylyl cyclase.
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Outline the differences between the Ras/MAPK pathway and the PI3K/Akt pathway. How are these pathways activated? What types of molecule each of these pathways? s are involved? What are the consequences of activation of
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