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please answer question 9
8 (3 pts.) In the section Designing the Drug Thalidomide", you learned...
8. In the section "Designing the Drug Thalidomide", you learned that researchers create various analogues to...
8. In the section "Designing the Drug Thalidomide", you
learned that researchers create various analogues to determine
which structural features are necessary for biological activity and
which are responsible for side effects. The analogues were created
using the molecule shown below. Using the information found in
Tabkw 3, sraw the corresponding analogs #7, 8, and 11.
9. Thalidomide is known to be an inhibitor of TBF-a. TNF-a is
a protein mediator, and when to much of this mediator is present,...
8. (3 pts.) In the section “designing the drug thalidomide”, you learned that researchers create various...
8. (3 pts.) In the section “designing the drug thalidomide”,
you learned that researchers create various analogs to determine
which structural features are necessary for biological activity and
which are responsible for side effects. the analogs were created
using the molecule shown below. using the information found in
table 3, draw the corresponding analogs #7, 8, and 11.
8. (3 pts.) In the section Designing the Drug Thalidomide" you learned that researchers create various analogs to determine which structural features...
7. (4 pts.) In Figure 3 of Section 4 “Designing the Drug Thalidomide”, two possible hydrolysis...
7. (4 pts.) In Figure 3 of Section 4 “Designing the Drug
Thalidomide”, two possible hydrolysis products are shown. Provide
the mechanism to generate compound 4. The first step of the
mechanism with the curved arrow pushing is done for you.
O + H-OH2 -N: Н. 0:0:- -NH2 N- 4 -ОН о о
Please write NEATLY and CLEARLY. (7.4 pts.) In Figure 3 of Section 4 “Designing the Drug...
Please write NEATLY and
CLEARLY.
(7.4 pts.) In Figure 3 of Section 4 “Designing the Drug Thalidomide”, two possible hydrolysis products are shown. Provide the mechanism to generate compound 4. The first step of the mechanism with the curved arrow pushing is done for you. + H-OH2 -N: :O: H -NH2 OH 0 SA H OH 5 -NH2 Figure 3: Possible biological degradtion products of thalidomide
8. In the section "Designing the Drug Thalidomide", you
learned that researchers create various analogues to determine
which structural features are necessary for biological activity and
which are responsible for side effects. The analogues were created
using the molecule shown below. Using the information found in
Tabkw 3, sraw the corresponding analogs #7, 8, and 11.
9. Thalidomide is known to be an inhibitor of TBF-a. TNF-a is
a protein mediator, and when to much of this mediator is present,...
8. (3 pts.) In the section “designing the drug thalidomide”,
you learned that researchers create various analogs to determine
which structural features are necessary for biological activity and
which are responsible for side effects. the analogs were created
using the molecule shown below. using the information found in
table 3, draw the corresponding analogs #7, 8, and 11.
8. (3 pts.) In the section Designing the Drug Thalidomide" you learned that researchers create various analogs to determine which structural features...
7. (4 pts.) In Figure 3 of Section 4 “Designing the Drug
Thalidomide”, two possible hydrolysis products are shown. Provide
the mechanism to generate compound 4. The first step of the
mechanism with the curved arrow pushing is done for you.
O + H-OH2 -N: Н. 0:0:- -NH2 N- 4 -ОН о о
Please write NEATLY and
CLEARLY.
(7.4 pts.) In Figure 3 of Section 4 “Designing the Drug Thalidomide”, two possible hydrolysis products are shown. Provide the mechanism to generate compound 4. The first step of the mechanism with the curved arrow pushing is done for you. + H-OH2 -N: :O: H -NH2 OH 0 SA H OH 5 -NH2 Figure 3: Possible biological degradtion products of thalidomide
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