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8. (3 pts.) In the section “designing the drug thalidomide”,
you learned that researchers create various...
8. In the section "Designing the Drug Thalidomide", you learned that researchers create various analogues to...
8. In the section "Designing the Drug Thalidomide", you
learned that researchers create various analogues to determine
which structural features are necessary for biological activity and
which are responsible for side effects. The analogues were created
using the molecule shown below. Using the information found in
Tabkw 3, sraw the corresponding analogs #7, 8, and 11.
9. Thalidomide is known to be an inhibitor of TBF-a. TNF-a is
a protein mediator, and when to much of this mediator is present,...
please answer question 9 8 (3 pts.) In the section Designing the Drug Thalidomide", you learned...
please answer question 9
8 (3 pts.) In the section Designing the Drug Thalidomide", you learned that researchers create various analogs to determine which structural features are necessary for biological activity and which are responsible for side effects. The analogs were created using the molecule shown below. Using the information found in Table 3. draw the corresponding analogs #78, and 11 o N IHz NH2 IC 50.= 150 km Analog #7 "NH2 'NH2 OCHS KTOCH2CH3 "OCH₂ CH3 IC 5o =...
7. (4 pts.) In Figure 3 of Section 4 “Designing the Drug Thalidomide”, two possible hydrolysis...
7. (4 pts.) In Figure 3 of Section 4 “Designing the Drug
Thalidomide”, two possible hydrolysis products are shown. Provide
the mechanism to generate compound 4. The first step of the
mechanism with the curved arrow pushing is done for you.
O + H-OH2 -N: Н. 0:0:- -NH2 N- 4 -ОН о о
4. (1 pt.) This question is in reference to Table 1 found in Section 3 "Scientific...
4. (1 pt.) This question is in reference to Table 1 found in Section 3 "Scientific Results in Support of Thalidome Victims". Based on the results, what can you conclude about the teratogenicity of the racemic mixture versus RA enantiomers of thalidomide? 5. (1 pt.) This question is in reference to Table 2 found in Section 3 "Scientific Results in Support of Thalidomide Victims". What can you conclude about the inversion rate for the two enantiomers? Table 1: Teratogenicity of...
4. This question is in reference to Table 1 found in Section 3 "Scientific Results in...
4. This question is in reference to Table 1 found in Section 3
"Scientific Results in Support of Thalidomide Victims." Based on
the results, what can you conclude about the teratogenicity of the
racemic mixture versus R/S enantiomers of thalidomide?
5. This question is in reference to Table 2 found in Section 3
"Scientific Results in Support of Thalidomide Victims." What can
you conclude about the inversion rate for the two
enantiomers?
6. The rate of inversion 0.5 (hr-1) corresponds...
Learning Experiences, Section 3: (Units 8 - 11) Choose one of the learning experiences below and...
Learning Experiences, Section 3: (Units 8 - 11) Choose one of the learning experiences below and write a 250 or more words and be as detailed as possibe 1. Perform at least one exercise for each major muscle group on a stability ball. On another day, perform the same exercises in a stationary position (i.e., not on a stability ball.) Report the following. List the exercises you performed. Were you able to use the same weight on the stability ball?...
LO 2 8-47 Target costing Mercedes-Benz All Activity Vehicle (AAV)'3 Introduction During the recession beginning in...
LO 2 8-47 Target costing Mercedes-Benz All Activity Vehicle (AAV)'3 Introduction During the recession beginning in the early 1990s, Mercedes-Benz (MB) struggled with product development, cost efficiency, material purchasing, and problems in adapting to changing mar- kets. In 1993, these problems caused the worst sales slump in decades, and the luxury car maker lost money for the first time in its history. Since then, MB has streamlined the core business, re- duced parts and system complexity, and established simultaneous engineering...
Need answers. thank you VOCABULARY BUILDER Misspelled Words Find the words below that are misspelled; circle...
Need answers. thank you
VOCABULARY BUILDER Misspelled Words Find the words below that are misspelled; circle them, and then correctly spell them in the spaces provided. Then fill in the blanks below with the correct vocabulary terms from the following list. amino acids digestion clectrolytes nutrients antioxident nutrition basal metabolic rate extracellulare oxydation calories fat-soluble presearvatives catalist glycogen processed foods cellulose homeostasis saturated fats major mineral coenzyeme trace minerals diaretics metabolism water-soluable 1. Artificial flavors, colors, and commonly added to...
please complete the entire case study pertaining to cirrhosis and nursing, thank you. 3 Cirrhosis John...
please complete the entire case study pertaining to cirrhosis
and nursing, thank you.
3 Cirrhosis John Richards, 45 years old Primary Concept Nutrition Interrelated Concepts (In order of emphasis) I. Fluid and Electrolyte Balance 2. Perfusion 3. Cognition 4. Addiction 5. Clinical Judgment 6. Patient Education 7. Communication 8.Collaboration O 2016 Keith Rischer/www.KeithRN.com UNFOLDING Reasoning Case Study: STUDENT History of Present Problem: John Richards is a 4S year-old male who Cirrhosis presents to the emergency department (ED) with abdominal pain...
First, read the article on "The Delphi Method for Graduate Research." ------ Article is posted below...
First, read the article on "The Delphi Method for Graduate Research." ------ Article is posted below Include each of the following in your answer (if applicable – explain in a paragraph) Research problem: what do you want to solve using Delphi? Sample: who will participate and why? (answer in 5 -10 sentences) Round one questionnaire: include 5 hypothetical questions you would like to ask Discuss: what are possible outcomes of the findings from your study? Hint: this is the conclusion....
8. In the section "Designing the Drug Thalidomide", you
learned that researchers create various analogues to determine
which structural features are necessary for biological activity and
which are responsible for side effects. The analogues were created
using the molecule shown below. Using the information found in
Tabkw 3, sraw the corresponding analogs #7, 8, and 11.
9. Thalidomide is known to be an inhibitor of TBF-a. TNF-a is
a protein mediator, and when to much of this mediator is present,...
please answer question 9
8 (3 pts.) In the section Designing the Drug Thalidomide", you learned that researchers create various analogs to determine which structural features are necessary for biological activity and which are responsible for side effects. The analogs were created using the molecule shown below. Using the information found in Table 3. draw the corresponding analogs #78, and 11 o N IHz NH2 IC 50.= 150 km Analog #7 "NH2 'NH2 OCHS KTOCH2CH3 "OCH₂ CH3 IC 5o =...
7. (4 pts.) In Figure 3 of Section 4 “Designing the Drug
Thalidomide”, two possible hydrolysis products are shown. Provide
the mechanism to generate compound 4. The first step of the
mechanism with the curved arrow pushing is done for you.
O + H-OH2 -N: Н. 0:0:- -NH2 N- 4 -ОН о о
4. (1 pt.) This question is in reference to Table 1 found in Section 3 "Scientific Results in Support of Thalidome Victims". Based on the results, what can you conclude about the teratogenicity of the racemic mixture versus RA enantiomers of thalidomide? 5. (1 pt.) This question is in reference to Table 2 found in Section 3 "Scientific Results in Support of Thalidomide Victims". What can you conclude about the inversion rate for the two enantiomers? Table 1: Teratogenicity of...
4. This question is in reference to Table 1 found in Section 3
"Scientific Results in Support of Thalidomide Victims." Based on
the results, what can you conclude about the teratogenicity of the
racemic mixture versus R/S enantiomers of thalidomide?
5. This question is in reference to Table 2 found in Section 3
"Scientific Results in Support of Thalidomide Victims." What can
you conclude about the inversion rate for the two
enantiomers?
6. The rate of inversion 0.5 (hr-1) corresponds...
LO 2 8-47 Target costing Mercedes-Benz All Activity Vehicle (AAV)'3 Introduction During the recession beginning in the early 1990s, Mercedes-Benz (MB) struggled with product development, cost efficiency, material purchasing, and problems in adapting to changing mar- kets. In 1993, these problems caused the worst sales slump in decades, and the luxury car maker lost money for the first time in its history. Since then, MB has streamlined the core business, re- duced parts and system complexity, and established simultaneous engineering...
Need answers. thank you
VOCABULARY BUILDER Misspelled Words Find the words below that are misspelled; circle them, and then correctly spell them in the spaces provided. Then fill in the blanks below with the correct vocabulary terms from the following list. amino acids digestion clectrolytes nutrients antioxident nutrition basal metabolic rate extracellulare oxydation calories fat-soluble presearvatives catalist glycogen processed foods cellulose homeostasis saturated fats major mineral coenzyeme trace minerals diaretics metabolism water-soluable 1. Artificial flavors, colors, and commonly added to...
please complete the entire case study pertaining to cirrhosis
and nursing, thank you.
3 Cirrhosis John Richards, 45 years old Primary Concept Nutrition Interrelated Concepts (In order of emphasis) I. Fluid and Electrolyte Balance 2. Perfusion 3. Cognition 4. Addiction 5. Clinical Judgment 6. Patient Education 7. Communication 8.Collaboration O 2016 Keith Rischer/www.KeithRN.com UNFOLDING Reasoning Case Study: STUDENT History of Present Problem: John Richards is a 4S year-old male who Cirrhosis presents to the emergency department (ED) with abdominal pain...
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