Albinism (lack of skin pigmentation) is caused by a recessive mutation on one of the autosomal...

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Albinism (lack of skin pigmentation) is caused by a recessive mutation on one of the autosomal chromosomes. A man and woman,

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RECESSIVE MUTATION IS A TYPE OF MUTATION IN WHICH THERE WILL BE A VISBLE PHENOTYPIC CHANGE ONLY IF THE TWO ALLELES ARE AFFECTED.IF ONE ALLELE IS MUTANT AND OTHER ALLELE IS NORMAL THEN THERE WILL NOT BE A VISIBLE PHENOTYPIC CHANGE OF THAT MUTANT ALLELE.

SO HERE IT IS SAID THAT BOTH PARENTS ARE NORMAL .SO BOTH CARRIES ONE MUTANT ALLELE OF ALBINISM.BUT THERE WILL NOT BE A VISIBLE CHANGE IN THEIR BODY.

LETS TAKE A NORMAL ALLELE AS 'A' AND MUTANT ALLELE AS 'a' . A PERSON IS AFFECTED BY ALBINISM ONLY IN 'aa' CONDITION. A PERSON WILL BE NORMAL IN 'AA' AND 'Aa' CONDITION.

SO LETS ASSUME FATHERS GENOTYPE AS Aa AND MOTHRERS GENOTYPE AS Aa .

Aa * Aa THE PROGENIES PRODUCED ARE- AA , Aa , Aa ,aa.

SO AMONG THE CHILDRENS ONLY ONE CHILD WILL BE AFFECTED BY ALBINISM AND OTHER THREE ARE NORMAL.SO THE PROBABILITY OF SECOND CHILD AFFECTED BY ALBINISM IS 0%.

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