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D The following pedigree corresponds to two families that carry a non-threatening autosomal dominant condition. What are the

I know the answer is D, but can someone explain to me how to do this problem? Thanks.

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Answer #1

1. Answer: Option D is correct
Explanation:
The probability that II-3 to be heterozygous = 2/3
The probability that II-4 to be heterozygous = 2/3
If both of them are heterozygous,
The probability that their child is unaffected = 2/3 X 2/3 X 1/4 = 1/9

The probability that their child is affected = 1-1/9
= 8/9

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