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At what ratios of ATP/ADP will the inhibition of PFK-1 be most diminished and why? =...

At what ratios of ATP/ADP will the inhibition of PFK-1 be most diminished and why?

= High ratios because the high amount of ATP encourages the body to transport ATP elsewhere leading to lower inhibition

= High ratios because ADP inhibits PFK

= Low ratios because the adenosine nucleotides are disappearing        

= Low ratios because the nucleotide pool is constant so a low ratio indicates a high amount of ADP

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Option D, Low ratios because the nucleotide pool is constant so a low ratio indicates a high amount of ADP

Inhibition of PFK1 is most diminised means inhibition decreases and increasing in level of PFK. PFK is inhibited by high level of ATP/ADP but inhibition diminished by low level of ATP/ADP and nucleotide pool remain constant indicates high ADP.

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