Question

Which is incorrect descriptions of the genetic event initiated by the HIV reverse transcriptase (RT) upon the HIV infection?

Select one:

a. RT catalyzes initial synthesis of ssDNA using viral genomic RNA as the template.

b. The first RNA template is degraded after ssDNA synthesis.

c. The whole process is completed after synthesis of dsDNA.

d. tRNAs are adopted as the first primers.

e. None of these

Answer 1

The correct answer for this question is -

e) none of these.

EXPLANATION -

HIV is the human immunovirus which contain single stranded RNA as a genetic material.

It contain gene for Reverse transcriptase enzyme which involve in synthesis of DNA from RNA. The steps in flow chart given below -

1) tRNA adopted as primer and bind to PBS( primer binding site) for hybrid .

2) Reverse transcriptase add DNA nucleaotide at 3 ' end primer and form complementry DNA.

3) RNAse -H which is a domain of RT degrade RNA template mostly except PP element.

4) again new DNA strand synthesis with RNA primer(pp sequence) on previous stand formed hence double strand of DNA formed

conclusion - from above discussion it is clear that all option a) , b ) , c) and d) is correct hence non of these is incorrect. And the correct option is - e) non of these.