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The ____ ring is built onto ribose-5-phosphate of PRPP for its de-novo nucleotide biosynthesis, while the...

The ____ ring is built onto ribose-5-phosphate of PRPP for its de-novo nucleotide biosynthesis, while the ring structure of the ______ bases are synthesized separately and then coupled to ribose-5-phosphate via the C-N glycosidic bond.

Select one:

a. inosine : adenine

b. inosine : uracil

c. uracil : inosine

d. uracil : adenine

e. None of these

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Answer #1

1. Answer: Option B is correct
Explanation:
For de-novo purine biosynthesis, the Ionosine ring is synthesized on to the ribose-5-phosphate of PRPP.
IMP ------> AMP
IMP ------> GMP

Pyrimidine bases are synthesized separately and coupled to ribose-5-phosphate via the C1-N glycosidic linkage.

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