Homework Answers
True
G proteins(made up of 3 subunits-G alpha,G beta and G gamma) associated with the inner side of membrane and transmembrane receptors of hormones also known as G protein coupled receptors(GPCRs) are called G proteins because they bind the GDP and GTP.GDP remain present in the binding site(inactive) of G alpha so whenever any hormone comes in contact with GPCR there is an allosteric structural change in the G alpha causing the release of GDP then replaced by GTP which in turn activates G alpha.Thereafter activated G alpha seprate itself from G beta and G gamma and actiavtes the another effector molecule which will convey the message of the respective hormone.
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In order to convert to the active state, a G protein must catalyze the addition of...
Question 13 0.5 pts Protein phosphorylation is catalyzed by? Protein kinase Protein Phosphatase Antibodies Antigens None...
Question 13 0.5 pts Protein phosphorylation is catalyzed by? Protein kinase Protein Phosphatase Antibodies Antigens None of the above Question 14 0.5 pts In an aqueous solution, which amino acid will orient itself inside the center of the protein? Valine Aspartic Acid Arginine Serine Glutamine Question 15 0.5 pts Enzymes in the enzyme class "kinase": Break down nucleic acids by hydrolying bonds between nucleotides O Catalyze the addition of phosphate groups to molecules Break down proteins by hydrolyzing peptide bonds...
Which answer is FALSE. The Ras protein, a prototype for all G proteins: A. must...
Which answer is FALSE. The Ras protein, a prototype for all G proteins: A. must bind a GTPase activator protein for hydrolysis of GTP to GDP B. has two critical residues that H-bond with the γ-phosphate of GTP C. holds the γ-phosphate of GTP in the P loop
Fbx25 is transcribed and processed in the nucleus and translated in the cytoplasm. Thus, the mRNA...
Fbx25 is transcribed and processed in the nucleus and translated in the cytoplasm. Thus, the mRNA must leave the nucleus using the G-protein Ran. Which of the following is true of G-proteins? They are active when bound to GTP They are active when bound to GDP. They actively synthesize GTP from GDP and phosphate They are activated by GAPs and deactivated by GEFs
Activity 4. Receptor signaling pathway A model of a G protein receptor signaling pathway is represented...
Activity 4. Receptor signaling pathway A model of a G protein receptor signaling pathway is represented below. Activation of the signaling pathway results in a cell secreting a neurotransmitter through exocytosis. Activated - Activated adenylyl receptor cyclase GTP АТР CAMP Active G protein Protein- kinase A Inactive Active Protein targets Phosphate group A. Different steps in a signaling pathway can amplify the initial signal of one ligand binding to one receptor. Choose one step in the pathway below that results...
3. Think about what G-proteins look like before they bind to a G-protein-coupled receptor. These G-proteins...
3. Think about what G-proteins look like before they bind to a G-protein-coupled receptor. These G-proteins would have...circle your answer GTP attached to them OR GDP attached to them (a) Think about what G-proteins look like after they bind to a G-protein-coupled receptor. These G-proteins would have...circle your answer GTP attached to them OR GDP attached to them (b) A molecule of GTP contains how many phosphate groups? (c) Think about a G-protein that has a GTP attached to it....
Only one G protein molecule can be activated by a single G protein-coupled receptor. True O...
Only one G protein molecule can be activated by a single G protein-coupled receptor. True O False Prosius
Ligand binding to a G-protein coupled receptor (GPCR) results in activation of a single G- protein...
Ligand binding to a G-protein coupled receptor (GPCR) results in activation of a single G- protein and then the receptor deactivates. O True False When an activated receptor relays the signal along more than one pathways this is called convergence. O True OFalse Which of the following best describes digestive enzymes? O Hydrolases OLigases Kinases Transferases Decarboxylases Most digestive enzymes are released from cells in an inactive form. True False denatures Protein digestion in humans (and other mammals) begins in...
NH HO HO Man Protein HO HO- Man or What type of membrane protein is shown...
NH HO HO Man Protein HO HO- Man or What type of membrane protein is shown below? Glycoprotein Man HO- HNo HO OR OH OM o0 wtracedular cell membrane eytesel Integral membrane protein GPI-anchored protein Peripheral membrane protein membrane proteins are bound primarily by electrostatic and hydrogen-bond interactions with the head groups of lipids. Peripheral membrane protein O Integral membrane protein GPI-anchored protein An antiporter and a symporter are examples of: passive diffusion Osecondary active transport O primary active transporters...
a. Alkenes with electron withdrawing groups are good dienophiles-True/False b. Wolfkishner reaction is helpful to convert an ester to alkane. True false c. Tertiary alcohol will be formed by the r...
a. Alkenes with electron withdrawing groups are good dienophiles-True/False b. Wolfkishner reaction is helpful to convert an ester to alkane. True false c. Tertiary alcohol will be formed by the reaction between a ketone and Grignard reagent True/ false d. A cyclic conjugated compound with 6 pi electron is aromatic- True/ False e. Addition of CO; to Methyl magnesium bromide is a nucleophilic addition Truel false f A good protecting group should be cleaved during the progress of the reaction-True...
In order to direct the proteins to the ER they must have added the nuclear localization...
In order to direct the proteins to the ER they must have added the nuclear localization signal (NLS) signal recognition particle (SRP) dolichol phosphate unit (DPU) ubiquitin recognition signal (URS) The purpose of dolichol phosphate is to assemble properly the protein in the ribosome introduce sugar units in the middle of a protein activate the protein for sugar addition carry the sugars to be introduced after protein synthesis Given the importance of glucagon in homeostasis, it must have a lot...
Question 13 0.5 pts Protein phosphorylation is catalyzed by? Protein kinase Protein Phosphatase Antibodies Antigens None of the above Question 14 0.5 pts In an aqueous solution, which amino acid will orient itself inside the center of the protein? Valine Aspartic Acid Arginine Serine Glutamine Question 15 0.5 pts Enzymes in the enzyme class "kinase": Break down nucleic acids by hydrolying bonds between nucleotides O Catalyze the addition of phosphate groups to molecules Break down proteins by hydrolyzing peptide bonds...
Activity 4. Receptor signaling pathway A model of a G protein receptor signaling pathway is represented below. Activation of the signaling pathway results in a cell secreting a neurotransmitter through exocytosis. Activated - Activated adenylyl receptor cyclase GTP АТР CAMP Active G protein Protein- kinase A Inactive Active Protein targets Phosphate group A. Different steps in a signaling pathway can amplify the initial signal of one ligand binding to one receptor. Choose one step in the pathway below that results...
3. Think about what G-proteins look like before they bind to a G-protein-coupled receptor. These G-proteins would have...circle your answer GTP attached to them OR GDP attached to them (a) Think about what G-proteins look like after they bind to a G-protein-coupled receptor. These G-proteins would have...circle your answer GTP attached to them OR GDP attached to them (b) A molecule of GTP contains how many phosphate groups? (c) Think about a G-protein that has a GTP attached to it....
Only one G protein molecule can be activated by a single G protein-coupled receptor. True O False Prosius
Ligand binding to a G-protein coupled receptor (GPCR) results in activation of a single G- protein and then the receptor deactivates. O True False When an activated receptor relays the signal along more than one pathways this is called convergence. O True OFalse Which of the following best describes digestive enzymes? O Hydrolases OLigases Kinases Transferases Decarboxylases Most digestive enzymes are released from cells in an inactive form. True False denatures Protein digestion in humans (and other mammals) begins in...
NH HO HO Man Protein HO HO- Man or What type of membrane protein is shown below? Glycoprotein Man HO- HNo HO OR OH OM o0 wtracedular cell membrane eytesel Integral membrane protein GPI-anchored protein Peripheral membrane protein membrane proteins are bound primarily by electrostatic and hydrogen-bond interactions with the head groups of lipids. Peripheral membrane protein O Integral membrane protein GPI-anchored protein An antiporter and a symporter are examples of: passive diffusion Osecondary active transport O primary active transporters...
a. Alkenes with electron withdrawing groups are good dienophiles-True/False b. Wolfkishner reaction is helpful to convert an ester to alkane. True false c. Tertiary alcohol will be formed by the reaction between a ketone and Grignard reagent True/ false d. A cyclic conjugated compound with 6 pi electron is aromatic- True/ False e. Addition of CO; to Methyl magnesium bromide is a nucleophilic addition Truel false f A good protecting group should be cleaved during the progress of the reaction-True...
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