Homework Answers
Answer- true because these are ligand specific and can bind to single G protein at a time. These produces signals for second messanger.
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Only one G protein molecule can be activated by a single G protein-coupled receptor. True O...
Ligand binding to a G-protein coupled receptor (GPCR) results in activation of a single G- protein...
Ligand binding to a G-protein coupled receptor (GPCR) results in activation of a single G- protein and then the receptor deactivates. O True False When an activated receptor relays the signal along more than one pathways this is called convergence. O True OFalse Which of the following best describes digestive enzymes? O Hydrolases OLigases Kinases Transferases Decarboxylases Most digestive enzymes are released from cells in an inactive form. True False denatures Protein digestion in humans (and other mammals) begins in...
3. Think about what G-proteins look like before they bind to a G-protein-coupled receptor. These G-proteins...
3. Think about what G-proteins look like before they bind to a G-protein-coupled receptor. These G-proteins would have...circle your answer GTP attached to them OR GDP attached to them (a) Think about what G-proteins look like after they bind to a G-protein-coupled receptor. These G-proteins would have...circle your answer GTP attached to them OR GDP attached to them (b) A molecule of GTP contains how many phosphate groups? (c) Think about a G-protein that has a GTP attached to it....
Assume that the binding of one molecule of epinephrine to a seven-transmembrane helix (7TM) receptor (also...
Assume that the binding of one molecule of epinephrine to a seven-transmembrane helix (7TM) receptor (also called the G protein-coupled receptor, or GPCR) results in the activation of 480 Gα subunits. In addition, suppose that each activated adenylyl cyclase catalyzes the conversion of 40 ATP molecules to cAMP per second. (Assume that each G protein activates a single unique adenylyl cyclase.) Calculate the number of moles of cAMP that are produced per second. Enter your answer to at least two...
The growth factor was a signalling molecule that bound to a receptor. channel Okinase O G-protein...
The growth factor was a signalling molecule that bound to a receptor. channel Okinase O G-protein contact-dependent Question 10 2 pts Which of the following best explains why dimerization of the kinase receptor in the absence of a growth factor could lead to cancer? The dimerization produces the growth factor, which can the signal for the cell to divide even if it was not supposed to. O Dimerization would cause the alpha subunit of a G-protein to become activated, leading...
Assume that the binding of one molecule of epinephrine to a seven‑transmembrane helix (7TM) receptor (also...
Assume that the binding of one molecule of epinephrine to a seven‑transmembrane helix (7TM) receptor (also called the G protein‑coupled receptor, or GPCR) results in the activation of 360 Gα360 Gα subunits. In addition, suppose that each activated adenylyl cyclase catalyzes the conversion of 30 ATP30 ATP molecules to cAMP per second. Assume that each G protein activates a single unique adenylyl cyclase. Calculate the number of moles of cAMP that are produced per second. Enter your answer to two...
Diagram the activation of the 5-HT Serotonin Receptor (G-Protein Coupled Receptor) leading to transcriptional activation in...
Diagram the activation of the 5-HT Serotonin Receptor (G-Protein Coupled Receptor) leading to transcriptional activation in a neuron. Include signaling pathways you have learned about in lecture or in your reading that involve G-Protein Coupled Receptors and lead to gene activation. Demonstrate how Lithium acts to disrupt one of these signaling pathways.
Diagram the activation of the 5-HT Serotonin Receptor (G-Protein Coupled Receptor) leading to transcriptional activation in...
Diagram the activation of the 5-HT Serotonin Receptor (G-Protein Coupled Receptor) leading to transcriptional activation in a neuron. Include signaling pathways you have learned about in lecture or in your reading that involve G- Protein Coupled Receptors and lead to gene activation. Demonstrate how Lithium acts to disrupt one of these signaling pathways. (20 points) 5.
1. What is the difference between: a. A G Protein and G Protein-Coupled Receptor b. Trimeric...
1. What is the difference between: a. A G Protein and G Protein-Coupled Receptor b. Trimeric and Monomeric G proteins
The opening of metabotropic G-protein-coupled receptor ion channels is faster than ionotropic transmitter-gated ion channels, triggering...
The opening of metabotropic G-protein-coupled receptor ion channels is faster than ionotropic transmitter-gated ion channels, triggering a wide- spread cellular metabolic effect. True False
Question 6 You and your G-protein coupled receptors o You have encountered G-protein coupled receptors in...
Question 6 You and your G-protein coupled receptors o You have encountered G-protein coupled receptors in Intro Bio I lecture (or soon will), and will encounter them briefly again in Intro Bio II. You will spend 2 or 3 lectures on them in Cell Bio. They are integral (transmembrane) proteins embedded in the plasma membrane of every eukaryotic cell in your body. We will treat them as being 50 Angstroms in diameter. Considering the plasma membrane scaled up to the...
Ligand binding to a G-protein coupled receptor (GPCR) results in activation of a single G- protein and then the receptor deactivates. O True False When an activated receptor relays the signal along more than one pathways this is called convergence. O True OFalse Which of the following best describes digestive enzymes? O Hydrolases OLigases Kinases Transferases Decarboxylases Most digestive enzymes are released from cells in an inactive form. True False denatures Protein digestion in humans (and other mammals) begins in...
3. Think about what G-proteins look like before they bind to a G-protein-coupled receptor. These G-proteins would have...circle your answer GTP attached to them OR GDP attached to them (a) Think about what G-proteins look like after they bind to a G-protein-coupled receptor. These G-proteins would have...circle your answer GTP attached to them OR GDP attached to them (b) A molecule of GTP contains how many phosphate groups? (c) Think about a G-protein that has a GTP attached to it....
The growth factor was a signalling molecule that bound to a receptor. channel Okinase O G-protein contact-dependent Question 10 2 pts Which of the following best explains why dimerization of the kinase receptor in the absence of a growth factor could lead to cancer? The dimerization produces the growth factor, which can the signal for the cell to divide even if it was not supposed to. O Dimerization would cause the alpha subunit of a G-protein to become activated, leading...
Diagram the activation of the 5-HT Serotonin Receptor (G-Protein Coupled Receptor) leading to transcriptional activation in a neuron. Include signaling pathways you have learned about in lecture or in your reading that involve G- Protein Coupled Receptors and lead to gene activation. Demonstrate how Lithium acts to disrupt one of these signaling pathways. (20 points) 5.
The opening of metabotropic G-protein-coupled receptor ion channels is faster than ionotropic transmitter-gated ion channels, triggering a wide- spread cellular metabolic effect. True False
Question 6 You and your G-protein coupled receptors o You have encountered G-protein coupled receptors in Intro Bio I lecture (or soon will), and will encounter them briefly again in Intro Bio II. You will spend 2 or 3 lectures on them in Cell Bio. They are integral (transmembrane) proteins embedded in the plasma membrane of every eukaryotic cell in your body. We will treat them as being 50 Angstroms in diameter. Considering the plasma membrane scaled up to the...
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